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阿尔茨海默病:巴西住院和死亡人数的流行病学分析。

Alzheimer's disease: an epidemiological analysis over the number of hospitalizations and deaths in Brazil.

机构信息

Universidade de Passo Fundo, Faculdade de Medicina, Passo Fundo RS, Brazil.

Instituto de Neurologia e Neurocirurgia de Passo Fundo, Passo Fundo RS, Brazil.

出版信息

Arq Neuropsiquiatr. 2023 Jun;81(6):577-584. doi: 10.1055/s-0043-1767827. Epub 2023 Jun 28.

DOI:10.1055/s-0043-1767827
PMID:37379869
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10306998/
Abstract

BACKGROUND

Alzheimer's disease (AD) is a neurodegenerative condition characterized by impaired cognitive function. It results in high morbidity, including a large number of hospitalizations, and mortality, generating high costs to health systems.

OBJECTIVE

The present epidemiological analysis evaluated the number of hospitalizations and deaths by AD as the main diagnosis in Brazil between 2010 and 2020. This endeavor should contribute to a better understanding of the disease and its implications.

METHODS

The present analytical, observational, longitudinal, and retrospective study used data extracted from the Department of Informatics of the Brazilian Unified Health System (DATASUS, in the Portuguese acronym). The variables include the number of hospitalizations, the total cost spent, the average cost per hospitalization, the average length of hospital stay, the number of deaths during hospitalization, the mortality rate per hospitalization, sex, age group, region, and race.

RESULTS

From 2010 to 2020, there were 188,811 deaths and 13,882 hospitalizations for AD, with a total expenditure of BRL 25,953,019.40 in hospitalizations. The average length of hospital stay was 25 days. Over the considered period, mortality, the number of hospitalizations, and the total cost increased while the average length of stay decreased.

CONCLUSION

From 2010 to 2020, AD represented a large portion of hospital admissions, generating a significant cost to the health system and a large number of deaths. These data are important to undertake joint efforts to prevent hospitalizations of these patients in order to minimize impacts on the health system.

摘要

背景

阿尔茨海默病(AD)是一种神经退行性疾病,其特征是认知功能受损。它导致高发病率,包括大量住院和死亡率,给卫生系统带来高昂成本。

目的

本流行病学分析评估了 2010 年至 2020 年期间巴西 AD 作为主要诊断的住院和死亡人数。这一努力应该有助于更好地了解该疾病及其影响。

方法

本分析性、观察性、纵向和回顾性研究使用了从巴西统一卫生系统信息部门(DATASUS,葡萄牙语缩写)提取的数据。变量包括住院人数、总花费、每次住院的平均费用、平均住院时间、住院期间死亡人数、每次住院的死亡率、性别、年龄组、地区和种族。

结果

2010 年至 2020 年期间,AD 导致了 188811 例死亡和 13882 例住院,住院总支出为 25953019.40 雷亚尔。平均住院时间为 25 天。在考虑的时期内,死亡率、住院人数和总费用增加,而平均住院时间减少。

结论

2010 年至 2020 年,AD 占住院人数的很大一部分,给卫生系统带来了巨大的成本和大量的死亡。这些数据对于共同努力防止这些患者住院以尽量减少对卫生系统的影响非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da1/10306998/bccf7d12c59b/10-1055-s-0043-1767827-i220155-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da1/10306998/5cc133265feb/10-1055-s-0043-1767827-i220155-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da1/10306998/f4f13812cc23/10-1055-s-0043-1767827-i220155-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da1/10306998/215a8cfe84f8/10-1055-s-0043-1767827-i220155-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da1/10306998/e65f819147b4/10-1055-s-0043-1767827-i220155-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da1/10306998/bccf7d12c59b/10-1055-s-0043-1767827-i220155-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da1/10306998/5cc133265feb/10-1055-s-0043-1767827-i220155-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da1/10306998/f4f13812cc23/10-1055-s-0043-1767827-i220155-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da1/10306998/215a8cfe84f8/10-1055-s-0043-1767827-i220155-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da1/10306998/e65f819147b4/10-1055-s-0043-1767827-i220155-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da1/10306998/bccf7d12c59b/10-1055-s-0043-1767827-i220155-5.jpg

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Front Public Health. 2021 Dec 24;9:784958. doi: 10.3389/fpubh.2021.784958. eCollection 2021.
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Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019.2019 年全球痴呆症患病率估计及 2050 年预测患病率:2019 年全球疾病负担研究分析。
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