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早产儿在矫正胎龄 6 个月和 12 个月时的神经心理运动发育。

Neuropsychomotor development in children born preterm at 6 and 12 months of corrected gestational age.

机构信息

Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.

出版信息

Rev Paul Pediatr. 2021 Sep 1;40:e2020199. doi: 10.1590/1984-0462/2022/40/2020199. eCollection 2021.

Abstract

OBJECTIVE

To assess the incidence of neuropsychomotor developmental delay at 6 and 12 months of corrected gestational age in children born at 32 gestational weeks or less.

METHODS

A descriptive and prospective study was carried out at two public maternity hospitals. Between April 2017 and January 2019, we assessed 133 children without any known risk factors for neuropsychomotor developmental delay. The Bayley III scale was used to evaluate cognitive and motor development. The p value of the numerical variables was calculated using the Mann-Whitney test, whereas proportions of categorical variables were compared using the Z-test.

RESULTS

The mean maternal age was 26±6.9 years,78.8% were from middle and lower economic classes, and 57.1% of the analyzed children were female. Children presented with a higher incidence of delay at 12 months than at 6 months (10.3 and 2.3% at 12 and 6 months, respectively, for the cognitive score; 22.7 and 12% at 12 and 6 months, respectively, for the composite motor score; and 24.7 and 8.4% at 12 and 6 months, respectively, for the fine motor score).

CONCLUSIONS

Cognitive and motor developmental delays were significant, with the highest incidence at 12 months. The results of this study encourage further research on this topic, since the exclusion criteria were comprehensive and the delays in neuropsychomotor development were significant.

摘要

目的

评估胎龄 32 周及以下出生的儿童在矫正胎龄 6 个月和 12 个月时神经心理运动发育迟缓的发生率。

方法

这是一项在两家公立医院进行的描述性和前瞻性研究。2017 年 4 月至 2019 年 1 月,我们评估了 133 名无神经心理运动发育迟缓已知危险因素的儿童。使用贝利 III 量表评估认知和运动发育。数值变量的 p 值使用曼-惠特尼检验计算,而分类变量的比例使用 Z 检验比较。

结果

母亲的平均年龄为 26±6.9 岁,78.8%来自中低经济阶层,分析的儿童中有 57.1%为女性。12 个月时儿童的发育迟缓发生率高于 6 个月时(认知评分分别为 12 个月和 6 个月时的 10.3%和 2.3%;综合运动评分分别为 12 个月和 6 个月时的 22.7%和 12%;精细运动评分分别为 12 个月和 6 个月时的 24.7%和 8.4%)。

结论

认知和运动发育迟缓明显,12 个月时发生率最高。本研究的结果鼓励进一步研究这一主题,因为排除标准全面,神经心理运动发育迟缓明显。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a3e/8432070/ee149d2df542/1984-0462-rpp-40-e2020199-gf01.jpg

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