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巨细胞动脉炎疑似病例中的神经梅毒。

Neurosyphilis in a suspected case of giant cell arteritis.

机构信息

Diabetes and Endocrinology, Mater Dei Hospital, Msida, Malta

Rheumatology and General Internal Medicine, Mater Dei Hospital, Msida, Malta.

出版信息

BMJ Case Rep. 2021 Sep 8;14(9):e242733. doi: 10.1136/bcr-2021-242733.

DOI:10.1136/bcr-2021-242733
PMID:34497053
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8438723/
Abstract

A 67-year-old man had a few month history of deteriorating visual acuity. He had originally presented to ophthalmology with right-sided visual blurring. This subsequently progressed to involve the left eye. At this point, he was empirically treated with high-dose glucocorticoids, both orally and intravenously, with the suspicion that giant cell arteritis was causing acute visual deterioration of his left eye. Unfortunately, his symptoms did not improve. During an admission to hospital for a pneumonia, he underwent further investigations for this bilateral visual loss. He was diagnosed with left neuroretinitis and right vitritis. A thorough workup revealed positive syphilis serology and cerebrospinal fluid was positive on venereal disease research laboratory testing. He was diagnosed and treated for neurosyphilis with intravenous benzylpenicillin 4 million units 4 hourly for 14 days. His left-sided vision improved but he still suffers from severe visual impairment in his right eye.

摘要

一位 67 岁男性出现数月视力逐渐下降的病史。他最初因右眼视力模糊就诊于眼科。随后左眼也出现同样的症状。此时,他经验性地接受了大剂量糖皮质激素(口服和静脉)治疗,疑似巨细胞动脉炎导致左眼急性视力下降。然而,他的症状并未改善。在因肺炎住院期间,他因双侧视力丧失进一步接受了检查。他被诊断为左眼神经视网膜炎和右眼玻璃体炎。全面检查发现梅毒血清学阳性,性病研究实验室检查脑脊液阳性。他被诊断为神经梅毒,并接受了 14 天的静脉注射苄星青霉素 400 万单位、每 4 小时 1 次的治疗。他的左眼视力有所改善,但右眼仍严重视力受损。

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本文引用的文献

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An Old Disease With an Unfamiliar Face: A Case Report of Ocular Syphilis.一张陌生面孔的古老疾病:一例眼梅毒病例报告
J Med Cases. 2020 Mar;11(3):77-78. doi: 10.14740/jmc3438. Epub 2020 Mar 26.
2
Eyes As the Window to Syphilis: A Rare Case of Ocular Syphilis As the Initial Presentation of Syphilis.眼睛作为梅毒的窗口:一例罕见的以眼部梅毒为梅毒首发表现的病例
Cureus. 2020 Feb 14;12(2):e6998. doi: 10.7759/cureus.6998.
3
Ocular syphilis in an immunocompetent host.免疫功能正常宿主的眼部梅毒
IDCases. 2019 Dec 26;19:e00684. doi: 10.1016/j.idcr.2019.e00684. eCollection 2020.
4
Ocular and neurosyphilis: epidemiology and approach to management.眼与神经梅毒:流行病学与处理方法。
Curr Opin Infect Dis. 2020 Feb;33(1):66-72. doi: 10.1097/QCO.0000000000000617.
5
Clinical Manifestations and Ophthalmic Outcomes of Ocular Syphilis at a Time of Re-Emergence of the Systemic Infection.临床症状与再发全身性感染时眼部梅毒的眼后表现和眼部结局。
Sci Rep. 2018 Aug 13;8(1):12071. doi: 10.1038/s41598-018-30559-7.
6
Analysis of 2 Reverse Syphilis Testing Algorithms in Diagnosis of Syphilis: A Large-Cohort Prospective Study.2 种梅毒反向检测算法在梅毒诊断中的分析:一项大型前瞻性队列研究。
Clin Infect Dis. 2018 Aug 31;67(6):947-953. doi: 10.1093/cid/ciy198.
7
Ophthalmic manifestations of giant cell arteritis.巨细胞动脉炎的眼部表现。
Rheumatology (Oxford). 2018 Feb 1;57(suppl_2):ii63-ii72. doi: 10.1093/rheumatology/kex428.
8
Neurosyphilis and ocular syphilis clinical and cerebrospinal fluid characteristics: a case series.神经梅毒和眼梅毒的临床及脑脊液特征:病例系列
Arq Neuropsiquiatr. 2018 Jun;76(6):373-380. doi: 10.1590/0004-282X20180054.
9
Three cases of ocular syphilis and the resurgence of the disease in Queensland.昆士兰州的三例眼梅毒病例及该疾病的再度出现。
Int Med Case Rep J. 2016 Sep 9;9:279-83. doi: 10.2147/IMCRJ.S111349. eCollection 2016.
10
Yellowish dots in the retina: a finding of ocular syphilis?视网膜上的淡黄色斑点:眼部梅毒的一种表现?
Arq Bras Oftalmol. 2014 Oct;77(5):324-326. doi: 10.5935/0004-2749.20140081.