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免疫功能正常宿主的眼部梅毒

Ocular syphilis in an immunocompetent host.

作者信息

Roy Moni, Roy Ashish K, Farrell John J

机构信息

OSF Saint Francis Medical Center, Peoria, IL, USA.

University Of Illinois College of Medicine, Department of Medicine, Peoria, IL, USA.

出版信息

IDCases. 2019 Dec 26;19:e00684. doi: 10.1016/j.idcr.2019.e00684. eCollection 2020.

DOI:10.1016/j.idcr.2019.e00684
PMID:32099808
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7030984/
Abstract

Syphilis is an old disease that experienced a resurgence with the emergence of HIV/AIDS. Syphilis is a reportable infection that is monitored by the Centers for disease Control (CDC) in the U.S. and rates have been rising since 2000. Although ocular syphilis is a well known consequence of syphilis infection it continues to be less frequently diagnosed, partially because ocular manifestations are not reportable to CDC. While the majority of recent cases in the U.S. have been reported in men who have sex with men (MSM) population, 50 % of these cases are HIV negative. We present a case of acute iridocyclitis and ocular hypertension due to syphilis infection. This case reiterates the need to increase healthcare workers' awareness of the importance of timely recognition of potential ocular syphilis to prevent visual sequelae from the infection. Ocular syphilis should be kept in the differential diagnosis in immunocompetent/HIV negative patients, and the importance of obtaining a detailed sexual history should not be forgotten.

摘要

梅毒是一种古老的疾病,随着艾滋病毒/艾滋病的出现而再度流行。梅毒是一种须上报的感染病,由美国疾病控制中心(CDC)进行监测,自2000年以来发病率一直在上升。虽然眼部梅毒是梅毒感染的一种众所周知的后果,但它仍然较少被诊断出来,部分原因是眼部表现无需向疾病控制中心上报。虽然美国最近的大多数病例报告发生在男男性行为者(MSM)人群中,但其中50%的病例艾滋病毒检测呈阴性。我们报告一例因梅毒感染导致急性虹膜睫状体炎和高眼压的病例。该病例重申了提高医护人员对及时识别潜在眼部梅毒重要性的认识的必要性,以防止感染导致的视觉后遗症。在免疫功能正常/艾滋病毒阴性的患者中,应将眼部梅毒纳入鉴别诊断,同时不应忘记获取详细性病史的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5afa/7030984/fac9de9f40cf/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5afa/7030984/8949bb6402a9/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5afa/7030984/fac9de9f40cf/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5afa/7030984/8949bb6402a9/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5afa/7030984/fac9de9f40cf/gr2.jpg

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本文引用的文献

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[Ocular syphilis, a re-emergent pathology: Series of 12 patients in one Hospital, 2017].[眼部梅毒,一种再度出现的病症:2017年一家医院的12例患者系列病例]
Rev Med Interne. 2020 Mar;41(3):160-167. doi: 10.1016/j.revmed.2019.06.006. Epub 2019 Jul 10.
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Normalization of serum rapid plasma reagin titer predicts normalization of cerebrospinal fluid and clinical abnormalities after treatment of neurosyphilis.血清快速血浆反应素滴度正常化预示着神经梅毒治疗后脑脊液及临床异常表现的正常化。
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