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神经梅毒在临床上和显微镜下均类似于巨细胞动脉炎。

Neurosyphilis mimicking giant cell arteritis both clinically and microscopically.

机构信息

Internal Medicine, Elisabeth-TweeSteden Ziekenhuis, Tilburg, The Netherlands.

Internal Medicine, Canisius Wilhelmina Hospital, Nijmegen, Gelderland, The Netherlands

出版信息

BMJ Case Rep. 2022 May 31;15(5):e247642. doi: 10.1136/bcr-2021-247642.

Abstract

Temporal arteritis is usually caused by giant cell arteritis (GCA). However, inflammation of the temporal artery can also occur secondary to autoimmune diseases or infections.We present a remarkable case of a man in his 70s with biopsy proven temporal arteritis, who was later diagnosed with meningovascular neurosyphilis. The presentation of an acute onset monocular vision loss with inflammation of the temporal artery on biopsy appeared a GCA, misleading the physicians, as it turned out to be a manifestation of neurosyphilis.

摘要

颞动脉炎通常由巨细胞动脉炎(GCA)引起。然而,颞动脉的炎症也可能继发于自身免疫性疾病或感染。我们报告了一例 70 多岁的男性,经活检证实为颞动脉炎,后来被诊断为脑膜血管性神经梅毒。急性单眼视力丧失和活检时颞动脉炎的表现看似为 GCA,这使医生产生了误解,因为事实证明这是神经梅毒的表现。

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本文引用的文献

1
Neurosyphilis presenting with a large vessel occlusion: A case report.以大血管闭塞为表现的神经梅毒:一例报告。
Brain Circ. 2021 Dec 21;7(4):285-288. doi: 10.4103/bc.bc_39_21. eCollection 2021 Oct-Dec.
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Neurosyphilis.神经梅毒
N Engl J Med. 2019 Oct 3;381(14):1358-1363. doi: 10.1056/NEJMra1906228.
4
Neurosyphilis in the modern era: Literature review and case series.神经梅毒的现代认识:文献复习与病例系列。
J Clin Neurosci. 2019 Nov;69:67-73. doi: 10.1016/j.jocn.2019.08.033. Epub 2019 Aug 16.
5
Treatment of giant cell arteritis.巨细胞动脉炎的治疗。
Biochem Pharmacol. 2019 Jul;165:230-239. doi: 10.1016/j.bcp.2019.04.027. Epub 2019 Apr 26.
7
Secondary Syphilis Mimicking Giant Cell Arteritis.
J Clin Rheumatol. 2020 Jan;26(1):18-20. doi: 10.1097/RHU.0000000000000764.
9
Neurosyphilis: from infection to autoinflammation?神经梅毒:从感染到自身炎症?
Int J STD AIDS. 2016 Mar;27(4):327-8. doi: 10.1177/0956462415590710.

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