Sobczyk W, Kulczycki J, Iwińska B, Buksowicz C, Piłkowska E
Kliniki Diagnostyki i Terapii Chorób Układu Nerwowego Instytutu Psychiatrii i Neurologii w Warszawie.
Neurol Neurochir Pol. 1987 Nov-Dec;21(6):516-9.
Seven patients with SSPE aged from 10 to 19 years received beta interferon intrathecally one million units every second day during one month (in all, 15 million units for one course of treatment. During the treatment signs were observed of irritation of the meninges which regressed after treatment completion. The neurological status of the patients was not significantly changed during the treatment. Control investigations carried out 3 to 10 months after the treatment demonstrated worsening with progression to a further phase of SSPE in 4 cases, and evidence of disease progression within the previous phase in 3 cases.
7例年龄在10至19岁的亚急性硬化性全脑炎（SSPE）患者，每隔一天鞘内注射100万单位β干扰素，持续一个月（一个疗程共1500万单位）。治疗期间观察到有脑膜刺激征，治疗结束后消退。治疗期间患者的神经状态无明显变化。治疗后3至10个月进行的对照研究表明，4例病情恶化并进展至SSPE的下一阶段，3例在前一阶段有疾病进展的迹象。
