Laczay Balint, Faulx Michael D
Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
J Clin Med. 2021 Aug 24;10(17):3785. doi: 10.3390/jcm10173785.
Obstructive sleep apnea (OSA) is a highly prevalent disorder with a growing incidence worldwide that closely mirrors the global obesity epidemic. OSA is associated with enormous healthcare costs in addition to significant morbidity and mortality. Much of the morbidity and mortality related to OSA can be attributed to an increased burden of cardiovascular disease, including cardiac rhythm disorders. Awareness of the relationship between OSA and rhythm disorders is variable among physicians, a fact that can influence patient care, since the presence of OSA can influence the incidence, prevalence, and successful treatment of multiple rhythm disorders. Herein, we provide a review of this topic that is intentionally broad in scope, covering the relationship between OSA and rhythm disorders from epidemiology and pathophysiology to diagnosis and management, with a particular focus on the recognition of undiagnosed OSA in the general clinical population and the intimate relationship between OSA and atrial fibrillation.
阻塞性睡眠呼吸暂停(OSA)是一种高度流行的疾病,在全球范围内发病率不断上升,这与全球肥胖流行情况密切相关。除了显著的发病率和死亡率外,OSA还带来了巨大的医疗成本。与OSA相关的许多发病率和死亡率可归因于心血管疾病负担的增加,包括心律失常。医生对OSA与心律失常之间关系的认识各不相同,这一事实可能会影响患者的治疗,因为OSA的存在会影响多种心律失常的发病率、患病率和成功治疗。在此,我们对该主题进行了综述,范围有意广泛,涵盖了从流行病学和病理生理学到诊断和管理的OSA与心律失常之间的关系,特别关注在普通临床人群中识别未诊断的OSA以及OSA与心房颤动之间的密切关系。