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试验性圆窗刺激对选择人工耳蜗植入治疗耳鸣患者的预后价值

Prognostic Value of Trial Round Window Stimulation for Selection of Candidates for Cochlear Implantation as Treatment for Tinnitus.

作者信息

Poels Laure, Zarowski Andrzej, Leblans Marc, Vanspauwen Robby, van Dinther Joost, Offeciers Erwin

机构信息

European Institute for ORL-HNS, Sint-Augustinus Hospital, 2610 Antwerp, Belgium.

出版信息

J Clin Med. 2021 Aug 25;10(17):3793. doi: 10.3390/jcm10173793.

DOI:10.3390/jcm10173793
PMID:34501241
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8432167/
Abstract

Electrical stimulation with cochlear implants is able to significantly suppress the tinnitus sensations in 25-72% of implanted patients. Up to this point, no clear predictors for the effectiveness of tinnitus suppression with cochlear implants have been found and this substantially limits the possibility of the application of cochlear implants for this purpose. The objective of the study was to investigate if a trial electrical round window stimulation (RWS) could be used as a diagnostic tool for identifying candidates in whom electrical stimulation would be successful as treatment for tinnitus. Thirty-four patients with unilateral severe tinnitus and ipsilateral moderate to severe sensorineural hearing loss underwent a trial RWS under local anesthesia. Thirteen patients received a cochlear implant. All patients qualified for cochlear implantation on the basis of the trial RWS showed tinnitus suppression with the implant switched on. Complete or almost complete tinnitus suppression was obtained in 77% and partial in 23%. The mean tinnitus loudness reduction was 68% (VAS score reduction from 7.7 to 2.5). False negative results are estimated not to exceed 10-15%. We conclude that significant tinnitus suppression achieved during trial RWS under local anesthesia is a simple procedure allowing the efficient identification of candidates in whom electrical stimulation with a cochlear implant would be successful as treatment for intractable tinnitus.

摘要

人工耳蜗电刺激能够显著减轻25%至72%植入患者的耳鸣症状。到目前为止,尚未发现明确的指标来预测人工耳蜗抑制耳鸣的效果,这在很大程度上限制了将人工耳蜗用于此目的的可能性。本研究的目的是调查试验性电圆窗刺激(RWS)是否可作为一种诊断工具,用于识别电刺激治疗耳鸣有效的患者。34例单侧严重耳鸣且同侧中度至重度感音神经性听力损失的患者在局部麻醉下接受了试验性RWS。13例患者接受了人工耳蜗植入。所有基于试验性RWS符合人工耳蜗植入条件的患者在人工耳蜗开机后耳鸣均得到减轻。77%的患者耳鸣完全或几乎完全消失,23%的患者部分减轻。耳鸣响度平均降低68%(视觉模拟评分从7.7降至2.5)。假阴性结果估计不超过10%至15%。我们得出结论,在局部麻醉下进行试验性RWS期间实现的显著耳鸣减轻是一种简单的程序,能够有效识别那些人工耳蜗电刺激治疗顽固性耳鸣有效的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/585e/8432167/1fc041067514/jcm-10-03793-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/585e/8432167/1fc041067514/jcm-10-03793-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/585e/8432167/1fc041067514/jcm-10-03793-g001.jpg

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引用本文的文献

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Tinnitus Suppression with Electrical Stimulation at the Most Basal Contact of the Cochlear Implant Electrode as a Model for Round Window Stimulation.电刺激耳蜗植入电极最基底接触点抑制耳鸣:一种圆窗刺激模型。
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2
Case report: Can cochlear implant stimulation lead to improved balance even after vestibular neurectomy?病例报告:即使在进行前庭神经切除术后,人工耳蜗刺激是否能改善平衡功能?
Front Neurol. 2023 Aug 25;14:1248715. doi: 10.3389/fneur.2023.1248715. eCollection 2023.
3
Technological Advances in the Diagnosis and Management of Tinnitus.

本文引用的文献

1
A multidisciplinary European guideline for tinnitus: diagnostics, assessment, and treatment.欧洲耳鸣多学科指南:诊断、评估与治疗
HNO. 2019 Mar;67(Suppl 1):10-42. doi: 10.1007/s00106-019-0633-7.
2
Tinnitus Suppression by Intracochlear Electrical Stimulation in Single-Sided Deafness: A Prospective Clinical Trial - Part I.单侧耳聋患者经耳蜗内电刺激抑制耳鸣:一项前瞻性临床试验 - 第一部分。
Audiol Neurootol. 2015;20(5):294-313. doi: 10.1159/000381936. Epub 2015 Jul 28.
3
The effect of cochlear implantation on tinnitus in patients with bilateral hearing loss: A systematic review.
耳鸣诊断与治疗的技术进展
J Clin Med. 2022 Aug 7;11(15):4597. doi: 10.3390/jcm11154597.
4
Conversations in Cochlear Implantation: The Inner Ear Therapy of Today.人工耳蜗植入中的对话:今日内耳治疗。
Biomolecules. 2022 Apr 29;12(5):649. doi: 10.3390/biom12050649.
人工耳蜗植入对双侧听力损失患者耳鸣的影响:一项系统评价。
Laryngoscope. 2015 Nov;125(11):2584-92. doi: 10.1002/lary.25370. Epub 2015 Jul 7.
4
Non-penetrating round window electrode stimulation for tinnitus therapy followed by cochlear implantation.非穿透性圆窗电极刺激用于耳鸣治疗,随后进行人工耳蜗植入。
Eur Arch Otorhinolaryngol. 2015 Nov;272(11):3283-93. doi: 10.1007/s00405-014-3413-8. Epub 2014 Dec 6.
5
Tinnitus.耳鸣。
Lancet. 2013 Nov 9;382(9904):1600-7. doi: 10.1016/S0140-6736(13)60142-7. Epub 2013 Jul 2.
6
Tinnitus suppression by electric stimulation of the auditory nerve.电刺激听神经抑制耳鸣。
Front Syst Neurosci. 2012 Mar 29;6:19. doi: 10.3389/fnsys.2012.00019. eCollection 2012.
7
Incapacitating unilateral tinnitus in single-sided deafness treated by cochlear implantation.人工耳蜗植入治疗单侧耳聋伴致残性单侧耳鸣
Ann Otol Rhinol Laryngol. 2008 Sep;117(9):645-52. doi: 10.1177/000348940811700903.
8
Tinnitus and cochlear implantation.耳鸣与人工耳蜗植入
Int J Audiol. 2004 May;43(5):245-51. doi: 10.1080/14992020400050033.
9
Electrical suppression of tinnitus.耳鸣的电抑制
Ciba Found Symp. 1981;85:217-31. doi: 10.1002/9780470720677.ch13.
10
First results of chronic electrical stimulation with a round-window electrode in totally deaf patients.完全失聪患者使用圆窗电极进行慢性电刺激的初步结果。
Arch Otorhinolaryngol. 1984;239(3):191-6. doi: 10.1007/BF00464243.