Poels Laure, Zarowski Andrzej, Leblans Marc, Vanspauwen Robby, van Dinther Joost, Offeciers Erwin
European Institute for ORL-HNS, Sint-Augustinus Hospital, 2610 Antwerp, Belgium.
J Clin Med. 2021 Aug 25;10(17):3793. doi: 10.3390/jcm10173793.
Electrical stimulation with cochlear implants is able to significantly suppress the tinnitus sensations in 25-72% of implanted patients. Up to this point, no clear predictors for the effectiveness of tinnitus suppression with cochlear implants have been found and this substantially limits the possibility of the application of cochlear implants for this purpose. The objective of the study was to investigate if a trial electrical round window stimulation (RWS) could be used as a diagnostic tool for identifying candidates in whom electrical stimulation would be successful as treatment for tinnitus. Thirty-four patients with unilateral severe tinnitus and ipsilateral moderate to severe sensorineural hearing loss underwent a trial RWS under local anesthesia. Thirteen patients received a cochlear implant. All patients qualified for cochlear implantation on the basis of the trial RWS showed tinnitus suppression with the implant switched on. Complete or almost complete tinnitus suppression was obtained in 77% and partial in 23%. The mean tinnitus loudness reduction was 68% (VAS score reduction from 7.7 to 2.5). False negative results are estimated not to exceed 10-15%. We conclude that significant tinnitus suppression achieved during trial RWS under local anesthesia is a simple procedure allowing the efficient identification of candidates in whom electrical stimulation with a cochlear implant would be successful as treatment for intractable tinnitus.
人工耳蜗电刺激能够显著减轻25%至72%植入患者的耳鸣症状。到目前为止,尚未发现明确的指标来预测人工耳蜗抑制耳鸣的效果,这在很大程度上限制了将人工耳蜗用于此目的的可能性。本研究的目的是调查试验性电圆窗刺激(RWS)是否可作为一种诊断工具,用于识别电刺激治疗耳鸣有效的患者。34例单侧严重耳鸣且同侧中度至重度感音神经性听力损失的患者在局部麻醉下接受了试验性RWS。13例患者接受了人工耳蜗植入。所有基于试验性RWS符合人工耳蜗植入条件的患者在人工耳蜗开机后耳鸣均得到减轻。77%的患者耳鸣完全或几乎完全消失,23%的患者部分减轻。耳鸣响度平均降低68%(视觉模拟评分从7.7降至2.5)。假阴性结果估计不超过10%至15%。我们得出结论,在局部麻醉下进行试验性RWS期间实现的显著耳鸣减轻是一种简单的程序,能够有效识别那些人工耳蜗电刺激治疗顽固性耳鸣有效的患者。