Tonko Johanna B, Wright Matthew J
Department of Cardiology, Guy's and St. Thomas' NHS Foundation Trust, London SE1 7EH, UK.
Faculty of Life Sciences and Medicine, King's College London, London SE1 1UL, UK.
J Clin Med. 2021 Aug 30;10(17):3922. doi: 10.3390/jcm10173922.
The high prevalence of atrial fibrillation (AF) in the overall population and its association with substantial morbidity, increased mortality and health care cost has instigated significant basic and clinical research efforts over recent years. The publication of multiple new high-quality randomized multi-center trials in the area of AF management and the rapidly evolving technological progress in terms of diagnostic possibilities and catheter ablation in recent years demanded a revision of the previous ESC AF Guidelines from 2016. The 2020 guidelines provide up-to-date, evidence-based guidance for the management of AF. One of the most important innovations is the presentation of a new concept for structural characterization of AF (the "4S AF scheme") replacing the traditional classification based on its temporal pattern alone (paroxysmal-persistent-permanent). The 4S-AF-scheme highlights the importance of systematic assessment of stroke risk, severity of symptoms, total AF burden and underlying substrate as the foundation for effective and individualized AF treatment for each and every patient. Further novelties relate to the presentation of an easy and intuitive management pathway ("ABC pathway") and strengthening the recommendations for early rhythm control, in particular the role of first line catheter ablation in heart failure. Another core component of the guidelines is the focus on patient involvement to achieve optimal outcomes. Patient education, shared decision making and incorporation of patient values and patient reported outcome of treatment interventions as well as integrated care by a multidisciplinary team all have a central role in the proposed management pathway for AF.
心房颤动(AF)在总体人群中的高患病率及其与高发病率、死亡率增加和医疗保健成本的关联,促使近年来开展了大量基础和临床研究工作。近年来,房颤管理领域发表了多项新的高质量随机多中心试验,且在诊断可能性和导管消融方面技术进步迅速,因此需要对2016年欧洲心脏病学会(ESC)房颤指南进行修订。2020年指南为房颤管理提供了最新的循证指导。其中最重要的创新之一是提出了一种用于房颤结构特征描述的新概念(“4S房颤方案”),取代了仅基于时间模式(阵发性-持续性-永久性)的传统分类方法。4S房颤方案强调了系统评估卒中风险、症状严重程度、房颤总负荷和潜在基质的重要性,将其作为为每位患者进行有效且个体化房颤治疗的基础。其他新内容包括呈现了一种简单直观的管理路径(“ABC路径”),以及强化了早期节律控制的建议,特别是一线导管消融在心力衰竭中的作用。该指南的另一个核心组成部分是注重患者参与以实现最佳治疗效果。患者教育、共同决策、纳入患者价值观和患者报告的治疗干预结果,以及多学科团队的综合护理,在拟议的房颤管理路径中均发挥着核心作用。