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减重手术后的门静脉肠系膜静脉血栓形成:一项在线调查

Portomesenteric Vein Thrombosis after Bariatric Surgery: An Online Survey.

作者信息

Carrano Francesco Maria, Weiner Sylvia, Elshafei Moustafa, Ahmed Saleem, Talishinskiy Toghrul, Tognoni Valeria, Mahawar Kamal, Di Lorenzo Nicola

机构信息

PhD Program in Applied Medical-Surgical Sciences, University of Rome "Tor Vergata", 00133 Rome, Italy.

Department of Surgical Sciences, University of Rome "Tor Vergata", 00133 Rome, Italy.

出版信息

J Clin Med. 2021 Sep 6;10(17):4024. doi: 10.3390/jcm10174024.

Abstract

Portomesenteric vein thrombosis (PMVT) is a rare post-operative complication of bariatric procedures, occurring in between 0.3% and 1% of cases. A structured questionnaire consisting of 27 items was available online to members of the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) to investigate the occurrence of PMVT. A total of 89 bariatric surgeons from 61 countries participated. Twenty-six (29.21%) reported at least one case of PMVT (46.15% males; 53.84% females). The surgery most associated with PMVT occurrence was sleeve gastrectomy (84.6%), followed by Roux-en-Y gastric bypass (RYGB) (7.69%), and laparoscopic adjustable gastric banding (LAGB) (7.69%). The time gap between surgery and PMVT was 19.28 ± 8.72 days. The predominant symptom was abdominal pain in 96.15% of patients, followed by fever in 26.9%. Complete occlusion of the portal vein was reported in 34.6% of cases, with involvement of the portal system in 69%, extension to the superior mesenteric district in 23%, and extension to the splenic vein in two patients (7.7%). Our survey, which is the largest regarding PMVT to date, revealed a diffuse lack of standardization in the choice, duration, and dosing of prophylaxis regimens as well as treatment modalities, reflecting the literature gap on the topic.

摘要

门静脉肠系膜静脉血栓形成(PMVT)是减肥手术罕见的术后并发症,发生率在0.3%至1%之间。国际肥胖与代谢疾病外科联合会(IFSO)的成员可在网上获取一份包含27个项目的结构化问卷,以调查PMVT的发生情况。共有来自61个国家的89名减肥外科医生参与。26名(29.21%)医生报告了至少1例PMVT(男性占46.15%;女性占53.84%)。与PMVT发生最相关的手术是袖状胃切除术(84.6%),其次是Roux-en-Y胃旁路术(RYGB)(7.69%),以及腹腔镜可调节胃束带术(LAGB)(7.69%)。手术与PMVT之间的时间间隔为19.28±8.72天。主要症状是96.15%的患者出现腹痛,其次是26.9%的患者发热。34.6%的病例报告门静脉完全闭塞,69%累及门静脉系统,23%延伸至肠系膜上区,两名患者(7.7%)延伸至脾静脉。我们的调查是迄今为止关于PMVT规模最大的一次,结果显示在预防方案的选择、持续时间和剂量以及治疗方式方面普遍缺乏标准化,这反映了该主题在文献方面的空白。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e60d/8432580/2adae1747c0a/jcm-10-04024-g0A1a.jpg

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