Benhamou D, Lorino A M, Lorino H, Zerah F, Harf A
Département d'Anesthésiologie, Hôpital de Bicêtre, Kremlin.
Bull Eur Physiopathol Respir. 1987 Sep-Oct;23(5):423-8.
The automated multilinear regression analysis method (MLRA) was recently proposed to measure respiratory mechanics in mechanically ventilated subjects [11]. The method is applicable whatever the inspiratory flow pattern and without any assumption as to the value of the parameter characterizing the non linear term of flow resistance. It was compared here in ten mechanically ventilated patients to the constant flow inflation (CFIM) method described by Rossi et al. [15]. The non linear term of flow resistance was lower in intubated patients than in corresponding isolated endotracheal tubes. When derived from the MLRA method, the values for the elastance of the respiratory system were significantly higher (p less than 0.01) than with the CFIM method, and those for the system resistance, significantly lower (p less than 0.01). These differences might be due to the recruitment of lung units in the early part of inflation. When additional resistances were inserted into the respiratory circuit, both methods proved able to determine their values accurately. They therefore appear suitable for respiratory resistance monitoring in anaesthetized ventilated patients.
自动多线性回归分析方法（MLRA）最近被提出用于测量机械通气患者的呼吸力学[11]。该方法适用于任何吸气流量模式，且无需对表征流阻非线性项的参数值做任何假设。在此将其与Rossi等人[15]描述的恒流充气法（CFIM）在10例机械通气患者中进行比较。插管患者的流阻非线性项低于相应的孤立气管内导管。从MLRA方法得出的呼吸系统弹性值显著高于CFIM方法（p<0.01），而系统阻力值则显著低于CFIM方法（p<0.01）。这些差异可能是由于充气早期肺单位的复张。当在呼吸回路中插入额外阻力时，两种方法都能准确测定其值。因此，它们似乎适用于麻醉通气患者的呼吸阻力监测。
