Department of Clinical Pharmacy and Pharmacy Administration, Faculty of Pharmacy, University of Ibadan, Ibadan, Nigeria.
BMC Med Educ. 2021 Sep 10;21(1):488. doi: 10.1186/s12909-021-02912-4.
Inappropriate use of antibiotics is a major cause of antimicrobial resistance (AMR). Inadequate knowledge about AMR among healthcare students could affect their practice of antimicrobial stewardship as future healthcare professionals. This study aims to assess the use of antibiotics and knowledge of AMR among future healthcare professionals of a Nigerian University.
Respondents' knowledge of antimicrobial resistance, use of antibiotics, and source of antibiotics in the past 12 months was explored using a self-administered questionnaire. Multivariate analyses were used to evaluate the relationship between specific variables and respondents' knowledge.
Of the 939 questionnaires administered to the students, 866 were filled given a response rate of 92.2 %. A total of (765; 88.3 %) of the respondents were aware that antimicrobial resistance makes it harder to eliminate the infection from the body as existing drugs become less effective. In all 824, (95.2 %) of the respondents had use antibiotics in the past 12 months. The use of antibiotics to treat malaria was self-reported by (175; 21.2 %). About half (432; 52.4 %) purchased the antibiotics from community pharmacies, while others obtained their antibiotics from the hospitals (192; 23.3 %), patent medicine stores (150; 18.2 %), and friends and family (50; 6.1 %) in the last 12 months. In all 506, (58.4 %) had good knowledge of antimicrobial resistance. Logistic regression shows that students in 3rd to 6th year 9.29 [AOR = 9.29, 95 % CI: (3.7-22.96)], had greater knowledge of antimicrobial resistance.
The healthcare students demonstrated a moderate knowledge of AMR. This underscores the need to adopt several educational tactics to introduce the concepts of AMR to the students and ensure there are strict policies to regulate the flow of antibiotics.
抗生素的不恰当使用是导致抗菌药物耐药性（AMR）的主要原因。如果医疗保健专业的学生对抗菌药物耐药性的了解不足，可能会影响他们作为未来医疗保健专业人员对抗菌药物管理的实践。本研究旨在评估尼日利亚一所大学未来医疗保健专业人员对抗生素的使用情况和对抗菌药物耐药性的认识。
使用自填式问卷探讨了受访者对抗菌药物耐药性的认识、过去 12 个月内使用抗生素的情况以及抗生素的来源。采用多变量分析评估了特定变量与受访者知识之间的关系。
在向学生发放的 939 份问卷中，有 866 份被填写，回应率为 92.2%。共有 765 名（88.3%）受访者意识到，由于现有药物的效果降低，抗菌药物耐药性使得从体内消除感染变得更加困难。在过去 12 个月内，所有 824 名（95.2%）受访者都使用过抗生素。有 175 名（21.2%）受访者自行报告使用抗生素治疗疟疾。大约一半（432 名，52.4%）受访者从社区药店购买抗生素，而其他人则从医院（192 名，23.3%）、专利药商店（150 名，18.2%）和朋友和家人（50 名，6.1%）处获得抗生素。在过去 12 个月内，共有 506 名（58.4%）受访者对抗菌药物耐药性有较好的了解。Logistic 回归显示，第 3 至 6 年的学生对抗菌药物耐药性的认识更强[优势比（AOR）=9.29，95%置信区间（CI）：（3.7-22.96）]。
医疗保健专业的学生对抗菌药物耐药性有一定的认识。这表明需要采取多种教育策略向学生介绍抗菌药物耐药性的概念，并确保有严格的政策来规范抗生素的使用。
