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适应证和结局:玻璃体腔注气治疗有症状的玻璃体黄斑牵拉。

Indications and outcomes for intravitreal injection of CF gas for symptomatic vitreomacular traction.

机构信息

Eye Clinic, Cantonal Hospital Sankt Gallen, Rorschacherstrasse 95, 9007, Sankt Gallen, Switzerland.

Department of Ophthalmology, University of Basel, Basel, Switzerland.

出版信息

Sci Rep. 2021 Sep 10;11(1):18089. doi: 10.1038/s41598-021-97639-z.

DOI:10.1038/s41598-021-97639-z
PMID:34508148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8433203/
Abstract

To evaluate the indications and outcomes of perfluoropropane (C3F8) gas injection for symptomatic vitreomacular traction (VMT). A retrospective analysis of eyes with VMT treated with 0.3 mL of C3F8 gas was performed. Patients were not asked to posture after gas injection. In phakic patients, cataract surgery was performed simultaneously. Patients were examined after one week and one month postoperatively. Twenty-nine consecutive eyes of 26 patients with symptomatic VMT who underwent pneumatic vitreolysis were included. A complete posterior vitreous detachment was achieved in 18 eyes (62.1%) after a single gas injection at the final visit. The rate of posterior vitreous detachment was reduced significantly with the presence of epiretinal membrane (ERM) (p = 0.003). Three eyes formed a macular hole (MH) postoperatively and another eye developed a retinal detachment. Mean visual acuity increased significantly after one month (p < 0.008). Pneumatic vitreolysis is a viable option for treating VMT with few adverse events. Patient with concomitant ERM had a significantly lower success rate.

摘要

评估全氟丙烷 (C3F8) 气体注射治疗症状性玻璃体黄斑牵引 (VMT) 的适应证和结果。对 26 例 29 只接受 0.3ml C3F8 气体注射治疗的 VMT 患者进行回顾性分析。注气后未要求患者采取特殊体位。在有晶状体眼患者中,同时行白内障手术。术后一周和一个月进行检查。29 只连续眼的 26 例有症状的 VMT 患者接受了气动玻璃体切除术。在最后一次就诊时,单次注气后有 18 只眼(62.1%)完全发生后玻璃体脱离。有视网膜内膜(ERM)存在时,后玻璃体脱离率显著降低(p=0.003)。术后 3 只眼形成黄斑裂孔(MH),另 1 只眼发生视网膜脱离。一个月后平均视力显著提高(p<0.008)。气动玻璃体切除术是治疗 VMT 的一种可行方法,不良事件较少。伴有 ERM 的患者成功率显著降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c469/8433203/0d6e8b128ea0/41598_2021_97639_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c469/8433203/ac3d4d36f85c/41598_2021_97639_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c469/8433203/b8cc02944d70/41598_2021_97639_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c469/8433203/0d6e8b128ea0/41598_2021_97639_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c469/8433203/ac3d4d36f85c/41598_2021_97639_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c469/8433203/b8cc02944d70/41598_2021_97639_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c469/8433203/0d6e8b128ea0/41598_2021_97639_Fig3_HTML.jpg

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本文引用的文献

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Spektrum Augenheilkd. 2018;32(6):228-238. doi: 10.1007/s00717-017-0382-5. Epub 2017 Dec 11.
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Posterior Vitreous Detachment.玻璃体后脱离
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