Department of Radiology, Om hospital and Research Center, Chabahil, Kathmandu, Nepal.
Department of Obstetrics and Gynaecology, Om hospital and Research Center, Chabahil, Kathmandu, Nepal.
JNMA J Nepal Med Assoc. 2021 Apr 30;59(236):396-398. doi: 10.31729/jnma.6402.
Anencephaly is a condition in which there is an absence of skull and brain tissues. Absence of cranial vault mainly results because of defective neurulation. Absence of cerebral tissues may cause diminished heart size, due to decreased heart load causing various cardiac abnormalities. Here, we report a case of a primigravida lady at 17 weeks of gestation with misoprostol induced expulsion of fetus after ultrasonography revealed absence of brain tissue and calvarium above the orbits suggesting anencephaly. A 300g fetus was delivered which confirmed the ultrasound findings. The patient was discharged with advice for intake of folic acid beginning from 3 months before conception in future pregnancies. Neural tube defects can manifest within approximately 28 days of gestation which highlights the importance of oral folic acid intake before pregnancy.
无脑畸形是一种颅骨和脑组织缺失的情况。颅穹窿的缺失主要是由于神经管缺陷导致的。由于心脏负荷减少导致各种心脏异常，脑组织结构的缺失可能会导致心脏体积缩小。在这里，我们报告了一例 17 周妊娠的初产妇，超声检查显示无脑组织和眼眶上方的颅骨，提示无脑畸形，在使用米索前列醇引产。产下一个 300 克的胎儿，证实了超声检查的结果。患者出院，并建议在未来妊娠中提前 3 个月开始服用叶酸。神经管缺陷大约在妊娠 28 天内就会显现，这突出了怀孕前口服叶酸的重要性。
