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海洛因使用者的毒理学筛查:对药物滥用管理的启示

Toxicological screening in heroin users: implications for management of drug misuse.

作者信息

Skidmore C A, Robertson J R, Simpson D, Jarvie D R

出版信息

J R Coll Gen Pract. 1987 Sep;37(302):397-9.

Abstract

The toxicological screening of 200 urine samples from 55 known heroin users claiming to be abstinent revealed that in 18% of samples (24% of users tested) opiates were unexpectedly detected. Other substances, many of which were psychoactive drugs, were identified in 35% of samples. Cocaine was not detected in any samples. In addition, nicotine was found in 91% of users and caffeine in 44%. The data showed the presence of polydrug abuse in 29% of subjects and suggested there is an illegal supply of drugs originating from doctors' prescriptions. The requirement for more general use of toxicological screening and the implications of the results for management of drug takers in general practices are discussed.

摘要

对55名自称已戒毒的已知海洛因使用者的200份尿液样本进行毒理学筛查发现,18%的样本(24%接受检测的使用者)意外检测出阿片类药物。在35%的样本中鉴定出了其他物质,其中许多是精神活性药物。所有样本中均未检测出可卡因。此外,91%的使用者检测出尼古丁,44%检测出咖啡因。数据显示29%的受试者存在多药滥用情况,并表明存在源自医生处方的非法药物供应。文中讨论了更广泛使用毒理学筛查的必要性以及这些结果对普通医疗中药物使用者管理的影响。

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引用本文的文献

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Use of a drug-screening service in an inner-city teaching hospital.
Med J Aust. 1981 Feb 7;1(3):132-3. doi: 10.5694/j.1326-5377.1981.tb135384.x.
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Experience with a haemagglutination inhibition test for morphine detection in urine.
Ann Clin Biochem. 1985 Mar;22 ( Pt 2):211-2. doi: 10.1177/000456328502200219.
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Br Med J (Clin Res Ed). 1985 Feb 9;290(6466):425-8. doi: 10.1136/bmj.290.6466.425.
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Drug screening: evaluation of the Toxi-Lab TLC system.
Ann Clin Biochem. 1986 Jan;23 ( Pt 1):76-84. doi: 10.1177/000456328602300109.
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Experience with the use of the Toxi-Lab TLC system in screening for morphine/heroin abuse.
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