College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China; State Key Laboratory of Southwestern Chinese Medicine Resources, Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
State Key Laboratory of Southwestern Chinese Medicine Resources, Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China; Ethnic Medicine Academic Heritage Innovation Research Center, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Curr Opin Pharmacol. 2021 Oct;60:306-314. doi: 10.1016/j.coph.2021.07.018. Epub 2021 Sep 8.
The highlands evoke both fascination and awe. Regardless of the reason to live in the highlands, symptoms related to altitude sickness are unbearable because of low atmospheric pressure, low oxygen concentration, strong ultraviolet radiation, cold, and psychological factors. Food and herbal medicines and/or health-care foods have protected highland dwellers owing to their multisystem regulation. These versatile products combine health-care properties with medical values by enhancing immunity, relieving physical fatigue, improving sleep, and augmenting hypoxia tolerance, with rare side effects. We therefore aimed to provide a more comprehensive analysis of these nutraceuticals, which can be used to prevent and treat symptoms of altitude hypoxia in the Chinese market. Finally, we dissect a new perspective for their promotion and development from molecular aspects.
高原既让人着迷又令人敬畏。无论居住在高原的原因是什么，由于低气压、低氧气浓度、强紫外线辐射、寒冷和心理因素，与高原病相关的症状是难以忍受的。由于多系统调节，食物和草药以及/或保健食品保护了高原居民。这些多功能产品通过增强免疫力、缓解身体疲劳、改善睡眠和提高缺氧耐受性来结合保健特性和医疗价值，副作用很少。因此，我们旨在更全面地分析这些营养保健品，这些保健品可用于预防和治疗中国市场的高原缺氧症状。最后，我们从分子角度为它们的推广和发展提供了一个新的视角。
