Wang Shaohui, Hou Ya, Li Xuanhao, Meng Xianli, Zhang Yi, Wang Xiaobo
School of Ethnic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Front Pharmacol. 2021 Dec 23;12:765435. doi: 10.3389/fphar.2021.765435. eCollection 2021.
Rheumatoid arthritis (RA), an autoimmune disease of unknown etiology, is a serious threat to the health of middle-aged and elderly people. Although western medicine, traditional medicine such as traditional Chinese medicine, Tibetan medicine and other ethnic medicine have shown certain advantages in the diagnosis and treatment of RA, there are still some practical shortcomings, such as delayed diagnosis, improper treatment scheme and unclear drug mechanism. At present, the applications of artificial intelligence (AI)-based deep learning and cloud computing has aroused wide attention in the medical and health field, especially in screening potential active ingredients, targets and action pathways of single drugs or prescriptions in traditional medicine and optimizing disease diagnosis and treatment models. Integrated information and analysis of RA patients based on AI and medical big data will unquestionably benefit more RA patients worldwide. In this review, we mainly elaborated the application status and prospect of AI-assisted deep learning and cloud computation-oriented western medicine and traditional medicine on the diagnosis and treatment of RA in different stages. It can be predicted that with the help of AI, more pharmacological mechanisms of effective ethnic drugs against RA will be elucidated and more accurate solutions will be provided for the treatment and diagnosis of RA in the future.
类风湿关节炎(RA)是一种病因不明的自身免疫性疾病,严重威胁着中老年人的健康。虽然西医以及中医、藏医等传统医学和其他民族医学在RA的诊疗中显示出一定优势,但仍存在一些实际不足,如诊断延迟、治疗方案不当以及药物作用机制不明等。目前,基于人工智能(AI)的深度学习和云计算在医疗卫生领域引起了广泛关注,特别是在筛选传统医学中单一药物或方剂的潜在活性成分、靶点和作用途径以及优化疾病诊疗模式方面。基于AI和医学大数据对RA患者进行综合信息分析无疑将使全球更多的RA患者受益。在这篇综述中,我们主要阐述了面向西医和传统医学的AI辅助深度学习和云计算在RA不同阶段诊疗中的应用现状与前景。可以预见,借助AI,未来将阐明更多有效民族药物抗RA的药理机制,并为RA的治疗和诊断提供更精准的解决方案。