Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Department of Ophthalmology, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Korea; and.
Retina. 2022 Feb 1;42(2):298-305. doi: 10.1097/IAE.0000000000003303.
To elucidate the significance of en-face optical coherence tomography imaging of atypical epiretinal tissue (AET) in the lamellar macular hole (LMH).
This study involved 29 eyes of 29 patients who underwent surgical treatment for LMH with AET. Best-corrected visual acuity, metamorphopsia assessment (M-score), and optical coherence tomography were evaluated before and 6 months after surgery. The novel en-face optical coherence tomography parameters, such as the area of AET and hyperreflective fringe, were correlated with clinical factors before and after LMH surgery.
Preoperatively, hyperreflective fringe was noted in 25 (86.2%) patients. The splitting of the inner retina, disruption of the ellipsoid zone, the extent of foveal cavitation, symptom duration, and change in best-corrected visual acuity were correlated with the area of AET (all P < 0.05). Multivariate regression analysis revealed that a larger area of AET was associated with longer symptom duration and less improvement in postoperative vision (all P < 0.05).
The area of AET may represent the chronicity of LMH and is significantly associated with visual outcomes after LMH surgery. This novel en-face optical coherence tomography parameter can be used as a predictive factor for surgical outcomes in LMH with AET.
阐明层状黄斑裂孔（LMH）中不典型视网膜前膜（AET）的光相干断层扫描成像的意义。
本研究纳入了 29 例 29 只眼的患者，这些患者均因 AET 而行 LMH 手术治疗。在术前和术后 6 个月评估最佳矫正视力、变形评估（M 评分）和光相干断层扫描。将新的 AET 面积和高反射性条纹等光相干断层扫描参数与 LMH 手术前后的临床因素相关联。
术前，25 例（86.2%）患者存在高反射性条纹。内视网膜分裂、椭圆体带破坏、中心凹空洞程度、症状持续时间和最佳矫正视力变化与 AET 面积相关（均 P < 0.05）。多变量回归分析显示，AET 面积越大，症状持续时间越长，术后视力改善越少（均 P < 0.05）。
AET 面积可能代表 LMH 的慢性程度，与 LMH 手术后的视力结果显著相关。这种新的基于面的光相干断层扫描参数可作为 AET 合并 LMH 手术结果的预测因子。
