Mi Jian-Wei, Wang Jia-Qi, Liu Jie, Zhang Li-Xian, Du Hong-Wei, Zhao Dong-Qiang
Department of Gastroenterology, The Second Hospital of Hebei Medical University, Shijiazhuang, 050000, People's Republic of China.
Basic Medical College, Hebei Medical University, Shijiazhuang, 050000, People's Republic of China.
Int J Gen Med. 2021 Sep 2;14:5149-5157. doi: 10.2147/IJGM.S319762. eCollection 2021.
This study aimed to explore the clinical value of endoscopic ultrasonography (EUS) in the endoscopic resection of gastrointestinal stromal tumors (GISTs).
A retrospective study of 92 patients who were confirmed to have GISTs by endoscopic resection after EUS examination was conducted. The preoperative features of the EUS examination, ultrasound diagnosis, endoscopic resection methods, surgical procedures, complications, and complete degree of lesion resection were recorded. And 16 patients who were diagnosed by endoscopy and EUS and confirmed by surgical operation were included and analyzed in the subsequent part of the investigation (gastroscopy and EUS image analysis, EUS image and risk classification).
The preoperative diagnosis rate of EUS and postoperative pathological diagnosis of GISTs was 78.7% (85/108), and the presence of a non-homogeneous echo and liquid anechoic zone in GISTs often indicated higher risk ( < 0.05). There was a positive correlation between tumor size and risk ( < 0.05).
The endoscopic resection of GISTs is feasible and safe. EUS is of great significance for the diagnosis and risk assessment of GISTs and can assist in the endoscopic resection of GISTs.
本研究旨在探讨内镜超声检查(EUS)在胃肠道间质瘤(GIST)内镜切除术中的临床价值。
对92例经EUS检查后经内镜切除确诊为GIST的患者进行回顾性研究。记录EUS检查的术前特征、超声诊断、内镜切除方法、手术过程、并发症及病变切除的完整程度。在后续研究部分纳入并分析16例经内镜及EUS诊断并经手术证实的患者(胃镜及EUS图像分析、EUS图像及风险分类)。
EUS术前诊断GIST的准确率及术后病理诊断率为78.7%(85/108),GIST中不均匀回声及液性无回声区的存在常提示较高风险(<0.05)。肿瘤大小与风险呈正相关(<0.05)。
GIST的内镜切除可行且安全。EUS对GIST的诊断及风险评估具有重要意义,可协助GIST的内镜切除。