Akkus Gamze, Tetiker Tamer
Department of Internal Medicine, Cukurova University Medical Faculty, Adana 33170, Turkey.
World J Diabetes. 2021 Aug 15;12(8):1312-1324. doi: 10.4239/wjd.v12.i8.1312.
The alarming rise in the worldwide prevalence of obesity is paralleled by an increasing burden of type 2 diabetes mellitus (T2DM). Metabolic surgery is the most effective means of obtaining substantial and durable weight loss in individual obese patients with T2DM. There are randomized trials that justify the inclusion of metabolic surgery into the treatment algorithm for patients with T2DM, but remission rates of T2DM after metabolic surgery can display great variability.
To discuss the most commonly used surgical options including vertical sleeve gastrectomy, adjustable gastric banding, Roux-en-Y gastric bypass, and biliopancreatic diversion with duodenal switch.
We also report from observational and randomized controlled studies on rate of remission of T2DM after the surgical procedures.
In light of the recent findings, metabolic surgery is a safe and effective treatment option for obese patient with T2DM, but further studies are needed to clarify better the rate of diabetes remission.
In light of the recent findings, metabolic surgery is a safe and effective treatment option for obese patients with T2DM, but further studies are needed to clarify better the rate of diabetes remission.
全球肥胖患病率惊人上升的同时，2型糖尿病（T2DM）的负担也日益加重。代谢手术是使个体肥胖的T2DM患者实现显著且持久体重减轻的最有效方法。有随机试验证明将代谢手术纳入T2DM患者的治疗方案是合理的，但代谢手术后T2DM的缓解率差异很大。
讨论最常用的手术方式，包括垂直袖状胃切除术、可调节胃束带术、Roux-en-Y胃旁路术以及胆胰转流十二指肠转位术。
我们还汇报了关于这些手术操作后T2DM缓解率的观察性研究和随机对照研究。
根据最近的研究结果，代谢手术对于肥胖的T2DM患者是一种安全有效的治疗选择，但需要进一步研究以更好地明确糖尿病缓解率。
根据最近的研究结果，代谢手术对于肥胖的T2DM患者是一种安全有效的治疗选择，但需要进一步研究以更好地明确糖尿病缓解率。
