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代谢手术作为 2 型糖尿病的治疗选择:手术观点。

Metabolic Surgery as a Treatment Option for Type 2 Diabetes Mellitus: Surgical View.

机构信息

Michael E. DeBakey Department of Surgery, Baylor College of Medicine, One Baylor Plaza, MS: BCM 390, Houston, TX, 77030, USA.

出版信息

Curr Diab Rep. 2018 Sep 26;18(11):113. doi: 10.1007/s11892-018-1094-1.

DOI:10.1007/s11892-018-1094-1
PMID:30259228
Abstract

PURPOSE OF REVIEW

Type 2 diabetes mellitus (T2DM) is increasing in prevalence and associated with numerous metabolic complications leading to increased mortality and costs. Metabolic surgery, or surgery to treat T2DM and obesity, is effective at achieving remission from T2DM. This review discusses the most commonly used surgical options including the adjustable gastric band, the Roux-en-Y gastric bypass, the sleeve gastrectomy, and the biliopancreatic diversion with duodenal switch and their ability to treat and prevent T2DM.

RECENT FINDINGS

There is an increasing body of literature that justifies the inclusion of metabolic surgery into the treatment algorithm for patients with obesity and T2DM. Metabolic procedures should be performed at centers that offer comprehensive treatment of metabolic disorders and have expertise in gastrointestinal surgery. The incremental improvement in the quality and safety of metabolic surgery has significantly reduced the risk of serious post-operative complications. Metabolic surgery is a safe and effective treatment option for obese patients with T2DM.

摘要

目的综述

2 型糖尿病(T2DM)的发病率不断上升,与许多代谢并发症相关,导致死亡率和医疗成本增加。代谢手术,即治疗 T2DM 和肥胖症的手术,对于 T2DM 的缓解非常有效。本文讨论了最常用的手术选择,包括可调胃束带、胃旁路术、胃袖状切除术和胆胰分流加十二指肠转位术,以及它们治疗和预防 T2DM 的能力。

最新发现

越来越多的文献证明,代谢手术应该纳入肥胖和 T2DM 患者的治疗方案中。代谢手术应在提供代谢疾病综合治疗且具有胃肠道手术专业知识的中心进行。代谢手术的质量和安全性的不断提高,显著降低了严重术后并发症的风险。代谢手术是肥胖 T2DM 患者安全有效的治疗选择。

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Metabolic Surgery as a Treatment Option for Type 2 Diabetes Mellitus: Surgical View.代谢手术作为 2 型糖尿病的治疗选择:手术观点。
Curr Diab Rep. 2018 Sep 26;18(11):113. doi: 10.1007/s11892-018-1094-1.
2
[Interpretation of the International Joint Statement on Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes].[《关于代谢手术在2型糖尿病治疗流程中的国际联合声明》解读]
Zhonghua Wei Chang Wai Ke Za Zhi. 2017 Apr 25;20(4):372-377.
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Which predictors could effect on remission of type 2 diabetes mellitus after the metabolic surgery: A general perspective of current studies?哪些预测因素会影响代谢手术后2型糖尿病的缓解:当前研究的总体视角?
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引用本文的文献

1
Type 2 diabetes mellitus status in obese patients following sleeve gastrectomy or one anastomosis gastric bypass.肥胖患者行袖状胃切除术或单吻合口胃旁路术后 2 型糖尿病状态。
Sci Rep. 2021 Feb 24;11(1):4421. doi: 10.1038/s41598-021-83807-8.
2
Biliopancreatic Diversion in the Surgical Treatment of Morbid Obesity: Long-Term Results and Metabolic Consequences.胃旁路术在病态肥胖症治疗中的应用:长期结果和代谢后果。
Obes Surg. 2020 Nov;30(11):4234-4242. doi: 10.1007/s11695-020-04777-w. Epub 2020 Jun 19.
3
Comparative effectiveness of bariatric surgeries in patients with obesity and type 2 diabetes mellitus: A network meta-analysis of randomized controlled trials.

本文引用的文献

1
Economic Costs of Diabetes in the U.S. in 2017.2017 年美国糖尿病的经济成本。
Diabetes Care. 2018 May;41(5):917-928. doi: 10.2337/dci18-0007. Epub 2018 Mar 22.
2
Which postoperative complications matter most after bariatric surgery? Prioritizing quality improvement efforts to improve national outcomes.减重手术后哪些并发症最重要?优先进行质量改进工作以改善全国的结果。
Surg Obes Relat Dis. 2018 May;14(5):652-657. doi: 10.1016/j.soard.2018.01.008. Epub 2018 Jan 12.
3
Effect of Laparoscopic Sleeve Gastrectomy vs Laparoscopic Roux-en-Y Gastric Bypass on Weight Loss at 5 Years Among Patients With Morbid Obesity: The SLEEVEPASS Randomized Clinical Trial.
肥胖合并 2 型糖尿病患者的减重手术效果比较:一项随机对照试验的网络荟萃分析。
Obes Rev. 2020 Aug;21(8):e13030. doi: 10.1111/obr.13030. Epub 2020 Apr 14.
4
Metabolic and Endocrine Consequences of Bariatric Surgery.减肥手术的代谢和内分泌后果。
Front Endocrinol (Lausanne). 2019 Sep 19;10:626. doi: 10.3389/fendo.2019.00626. eCollection 2019.
腹腔镜袖状胃切除术与腹腔镜Roux-en-Y胃旁路术对病态肥胖患者5年体重减轻的影响:SLEEVEPASS随机临床试验
JAMA. 2018 Jan 16;319(3):241-254. doi: 10.1001/jama.2017.20313.
4
Weight and Metabolic Outcomes 12 Years after Gastric Bypass.胃旁路术后12年的体重及代谢结果
N Engl J Med. 2017 Sep 21;377(12):1143-1155. doi: 10.1056/NEJMoa1700459.
5
Modulation of the gut microbiome: a systematic review of the effect of bariatric surgery.肠道微生物群的调节:对减肥手术效果的系统评价
Eur J Endocrinol. 2018 Jan;178(1):43-56. doi: 10.1530/EJE-17-0403. Epub 2017 Sep 15.
6
American Society for Metabolic and Bariatric Surgery Integrated Health Nutritional Guidelines for the Surgical Weight Loss Patient 2016 Update: Micronutrients.美国代谢与减重外科学会《2016年手术减重患者综合健康营养指南更新:微量营养素》
Surg Obes Relat Dis. 2017 May;13(5):727-741. doi: 10.1016/j.soard.2016.12.018. Epub 2017 Jan 19.
7
Bariatric Surgery versus Intensive Medical Therapy for Diabetes - 5-Year Outcomes.减肥手术与强化药物治疗糖尿病——5年结果
N Engl J Med. 2017 Feb 16;376(7):641-651. doi: 10.1056/NEJMoa1600869.
8
Laparoscopic Sleeve Gastrectomy Versus Roux-Y-Gastric Bypass for Morbid Obesity-3-Year Outcomes of the Prospective Randomized Swiss Multicenter Bypass Or Sleeve Study (SM-BOSS).腹腔镜袖状胃切除术与Roux-Y胃旁路术治疗病态肥胖——前瞻性随机瑞士多中心旁路或袖状胃研究(SM-BOSS)的3年结果
Ann Surg. 2017 Mar;265(3):466-473. doi: 10.1097/SLA.0000000000001929.
9
Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass. Data from IFSO-European Chapter Center of Excellence Program.袖状胃切除术与Roux-en-Y胃旁路术。来自国际肥胖与代谢病外科联盟欧洲分会卓越中心项目的数据。
Obes Surg. 2017 Apr;27(4):847-855. doi: 10.1007/s11695-016-2395-6.
10
Long-term and midterm outcomes of laparoscopic sleeve gastrectomy versus Roux-en-Y gastric bypass: a systematic review and meta-analysis of comparative studies.腹腔镜袖状胃切除术与Roux-en-Y胃旁路术的长期和中期结局:比较研究的系统评价和荟萃分析
Surg Obes Relat Dis. 2017 Feb;13(2):170-180. doi: 10.1016/j.soard.2016.08.011. Epub 2016 Aug 18.