Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Department of Otorhinolaryngology - Head & Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Head Neck. 2021 Nov;43(11):3572-3585. doi: 10.1002/hed.26856. Epub 2021 Sep 13.
Whole-body hybrid positron emission tomography (PET) imaging is increasingly used for sinonasal tumors. However, only empirical data exist on the additional, clinically relevant information derived from these techniques.
This study included 96 regionalized magnetic resonance imaging (MRI) of the sinonasal tract/neck and separate hybrid FDG-PET/CT or FDG-PET/MRI in 74 patients. Additional radiological information (ARI) obtained from each hybrid examination was analyzed and its clinically relevance was determined. Clinically relevant information (CRI) was categorized with regard to primary tumor site, regional lymph node metastases, distant metastases, second primary tumors, and non-neoplastic findings.
A total of 45/96 (46.9%) hybrid PET examinations revealed ARI. CRI was found in 32/96 (33.3%) examinations and concerned the primary tumor site (6.1%), regional lymph node metastases (4.1%), distant metastases (14.3%), second primary tumors (7.3%), and non-neoplastic findings (5.1%).
Hybrid PET imaging yields additional radiological information translating into clinically relevant information in a substantial proportion of patients with sinonasal tumors.
全身混合正电子发射断层扫描（PET）成像越来越多地用于鼻腔鼻窦肿瘤。然而，这些技术所带来的额外、具有临床相关性的信息仅存在经验数据。
本研究纳入了 74 例患者的 96 例区域性磁共振成像（MRI）鼻腔鼻窦/颈部和单独的 FDG-PET/CT 或 FDG-PET/MRI。分析了每种混合检查获得的额外放射学信息（ARI），并确定了其临床相关性。临床相关信息（CRI）根据原发肿瘤部位、区域淋巴结转移、远处转移、第二原发肿瘤和非肿瘤性发现进行分类。
共有 45/96（46.9%）例混合 PET 检查显示 ARI。32/96（33.3%）例检查发现了 CRI，涉及原发肿瘤部位（6.1%）、区域淋巴结转移（4.1%）、远处转移（14.3%）、第二原发肿瘤（7.3%）和非肿瘤性发现（5.1%）。
混合 PET 成像在相当一部分鼻腔鼻窦肿瘤患者中产生了额外的放射学信息，这些信息转化为具有临床相关性的信息。
