Department of Mechanical Engineering, Yuan Ze University, Taoyuan 320, Taiwan.
Department of Electronics and Communication Engineering, Vellore Institute of Technology, Tamil Nadu 632014, India.
Math Biosci Eng. 2021 Jun 7;18(5):5047-5068. doi: 10.3934/mbe.2021257.
According to a recently conducted survey on surgical complication mortality rate, 47% of such cases are due to anesthetics overdose. This indicates that there is an urgent need to moderate the level of anesthesia. Recently deep learning (DL) methods have played a major role in estimating the depth of Anesthesia (DOA) of patients and has played an essential role in control anesthesia overdose. In this paper, Electroencephalography (EEG) signals have been used for the prediction of DOA. EEG signals are very complex signals which may require months of training and advanced signal processing techniques. It is a point of debate whether DL methods are an improvement over the already existing traditional EEG signal processing approaches. One of the DL algorithms is Convolutional neural network (CNN) which is very popular algorithm for object recognition and is widely growing its applications in processing hierarchy in the human visual system. In this paper, various decomposition methods have been used for extracting the features EEG signal. After acquiring the necessary signals values in image format, several CNN models have been deployed for classification of DOA depending upon their Bispectral Index (BIS) and the signal quality index (SQI). The EEG signals were converted into the frequency domain using and Empirical Mode Decomposition (EMD), and Ensemble Empirical Mode Decomposition (EEMD). However, because of the inter mode mixing observed in EMD method; EEMD have been utilized for this study. The developed CNN models were used to predict the DOA based on the EEG spectrum images without the use of handcrafted features which provides intuitive mapping with high efficiency and reliability. The best trained model gives an accuracy of 83.2%. Hence, this provides further scope and research which can be carried out in the domain of visual mapping of DOA using EEG signals and DL methods.
根据最近一项关于手术并发症死亡率的调查,47%的此类病例是由于麻醉过量引起的。这表明迫切需要调整麻醉水平。最近,深度学习(DL)方法在估计患者麻醉深度(DOA)方面发挥了重要作用,并在控制麻醉过量方面发挥了重要作用。在本文中,使用脑电图(EEG)信号来预测 DOA。EEG 信号是非常复杂的信号,可能需要数月的训练和先进的信号处理技术。DL 方法是否优于现有的传统 EEG 信号处理方法,这是一个有争议的问题。DL 算法之一是卷积神经网络(CNN),它是一种非常流行的用于对象识别的算法,并广泛应用于人类视觉系统中的处理层次。在本文中,使用了各种分解方法来提取 EEG 信号的特征。在以图像格式获取必要的信号值后,根据其双谱指数(BIS)和信号质量指数(SQI),部署了几个 CNN 模型来对 DOA 进行分类。EEG 信号使用经验模态分解(EMD)和集合经验模态分解(EEMD)转换为频域。然而,由于在 EMD 方法中观察到的模式间混合;因此,在这项研究中使用了 EEMD。开发的 CNN 模型用于根据 EEG 谱图像预测 DOA,而无需使用手工制作的特征,这提供了直观的映射,具有高效率和可靠性。经过最佳训练的模型的准确率为 83.2%。因此,这为使用 EEG 信号和 DL 方法进行 DOA 的视觉映射领域的进一步研究和研究提供了进一步的空间。