Specialty trainee, Oral Surgery, Cork University Dental School and Hospital, University College Cork, Cork, Ireland.
Consultant/Senior Lecturer, Oral Medicine, Cork University Dental School and Hospital, University College Cork, Cork, Ireland; Honorary Associate Professor, Oral Medicine, University College London, London Eastman Dental Institute, London, United Kingdom.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2022 Feb;133(2):156-164. doi: 10.1016/j.oooo.2021.05.013. Epub 2021 Sep 11.
Autologous platelet concentrates (APCs) are a relatively new phenomenon, with initial reports of their regenerative potential published as recently as 1998. Despite their relative infancy, a huge body of evidence exists in support of their capacity to promote osseous and soft tissue regeneration through the physiologic processes of platelet activation and subsequent growth factor release. APCs have transformed many areas of healthcare and are now considered an essential component of the surgical milieu. In this narrative review, we explore the evolution of autologous platelet therapies with a particular emphasis on their contemporary applications in oral surgery, which rather fittingly was the first specialty to report the regenerative potential of APCs.
自体血小板浓缩物（APCs）是一种相对较新的现象，其再生潜力的最初报道可以追溯到 1998 年。尽管它们还处于相对早期的阶段，但已经有大量证据支持它们通过血小板激活和随后的生长因子释放等生理过程促进骨和软组织再生的能力。APCs 已经改变了许多医疗保健领域，现在被认为是手术环境的重要组成部分。在这篇叙述性综述中，我们探讨了自体血小板治疗的发展，特别强调了它们在口腔外科中的当代应用，而口腔外科恰恰是第一个报告 APCs 再生潜力的专业领域。
