Booth T F, Beadle D J, Hart R J
School of Biological Sciences, Thames Polytechnic, London, Great Britain.
Exp Appl Acarol. 1986 Jun;2(2):187-98. doi: 10.1007/BF01213761.
Wax synthesis by Gené's organ, the egg waxing organ of ticks, is by precocene treatment of engorged female Boophilus microplus, resulting in desiccated nonviable eggs due to the absence of a waterproofing wax layer. Electron microscopy shows that precocene has a destructive effect on the glandular cells of Gené's organ. The precocene also inhibited in vitro wax synthesis by the gland cells, indicating a selective cytotoxic effect. Oogenesis and oviposition were otherwise unaffected, also suggesting that precocene affects the gland cells directly, rather than indirectly by antagonism of juvenile hormone.
蜱虫的卵蜡分泌器官——吉内氏器合成蜡质，通过对饱血的微小牛蜱雌虫进行早熟素处理，由于缺乏防水蜡层，导致卵干燥无法存活。电子显微镜显示，早熟素对吉内氏器的腺细胞有破坏作用。早熟素还在体外抑制腺细胞的蜡质合成，表明其具有选择性细胞毒性作用。卵子发生和产卵在其他方面未受影响，这也表明早熟素直接影响腺细胞，而非通过拮抗保幼激素间接产生影响。
