van Bronswijk J E
Department of Dermatology, University of Utrecht, The Netherlands.
Exp Appl Acarol. 1986 Sep;2(3):231-8. doi: 10.1007/BF01193955.
Since guanine is not only an essential constituent of vital nucleic acids, but also the main end product of nitrogenous waste excretion in arachnids, it is a potential candidate for a hygienic index for mite activity in house dust. The public health significance of these mites is based on their production of allergen in the home environment. In 101 mattress-dust samples, total number of mites and guanine content were positively correlated. The hygienic standard of 10 mites per 0.1 g dust (as derived from Danish investigations) was met in all samples with less than 0.06% guanine in the dry dust. Where the guanine content was more than or equal to 0.25% in the dry dust, mite numbers were higher than 10 mites per 0.1 g dust in 43 of the 44 samples. The three different groups (negligible mite content, possibly allergologically relevant mite concentration and allergologically unhygienic mite situation) could be easily discriminated on the color scale. The guanine-AZO-dye reaction in vacuum cleaner dust is a strong and promising candidate for an allergologically relevant hygienic index in the home.
由于鸟嘌呤不仅是重要核酸的必需成分，也是蛛形纲动物含氮废物排泄的主要终产物，它是室内灰尘中螨虫活动卫生指标的潜在候选物。这些螨虫对公共卫生的重要性基于它们在家庭环境中产生过敏原。在101份床垫灰尘样本中，螨虫总数与鸟嘌呤含量呈正相关。在所有干尘中鸟嘌呤含量低于0.06%的样本中，均符合每0.1克灰尘中有10只螨虫的卫生标准（源自丹麦的调查）。在44个样本中的43个样本中，当干尘中鸟嘌呤含量大于或等于0.25%时，螨虫数量高于每0.1克灰尘中有10只螨虫。通过颜色刻度可以轻松区分三个不同的组（螨虫含量可忽略不计、可能与过敏学相关的螨虫浓度以及过敏学上不卫生的螨虫情况）。吸尘器灰尘中的鸟嘌呤 - 偶氮染料反应是家庭中与过敏学相关的卫生指标的有力且有前景的候选物。
