Valenzuela-Iglesias Mia F, Ccama-Leiva J Lorena, Urrunaga-Pastor Diego, Runzer-Colmenares Fernando M, Parodi José F
Facultad de Ciencias de la Salud, Universidad Científica del Sur, Carrera de Medicina Humana, Lima, Peru.
Dirección de Investigación en Salud, Instituto de Evaluación de Tecnologías en Salud e Investigación-IETSI, EsSalud, Lima, Peru.
Int J Geriatr Psychiatry. 2021 Sep 14;37(1). doi: 10.1002/gps.5619.
Our objective was to evaluate the association between depressive symptoms and disability in older adults residing in 12 high Andean communities in Peru.
We carried out a secondary data analysis of a cross-sectional study that included older adults (60 years or older) from 12 high Andean communities in Peru from 2013 to 2019. Depressive symptoms were defined as a score of two or more in the abbreviated Geriatric Depression Scale, while disability was defined as a score of less than 95 in the Barthel index. We also included sociodemographic characteristics, medical and personal history, and functional and performance-based tests. We used crude and adjusted Poisson regression models to evaluate the association of interest and estimated prevalence ratios (PR) with their respective 95% confidence intervals (95% CI).
We included 442 older adults with a mean age of 73 ± 6.9 in the analysis; 63.1% (n = 279) were women, and 79.9% (n = 353) had no education or incomplete primary school. 50.9% (n = 225) of the participants had depressive symptoms, and 49.8% (n = 220) had disability. The adjusted Poisson regression model showed that depressive symptoms increased the probability of disability (adjusted PR = 1.67; 95% CI: 1.34-2.08; p < 0.001) in older adults living at high altitude.
Depressive symptoms was associated with a greater probability of disability in older adults living at high altitude. Longitudinal studies are needed for better understanding of this association in high altitude populations along with timely interventions to reduce the impact of both geriatric syndromes.
我们的目的是评估居住在秘鲁12个安第斯高原社区的老年人抑郁症状与残疾之间的关联。
我们对一项横断面研究进行了二次数据分析，该研究纳入了2013年至2019年来自秘鲁12个安第斯高原社区的老年人（60岁及以上）。抑郁症状被定义为简易老年抑郁量表得分达到两分或更高，而残疾被定义为巴氏指数得分低于95分。我们还纳入了社会人口学特征、医疗和个人病史以及基于功能和表现的测试。我们使用粗泊松回归模型和调整后的泊松回归模型来评估感兴趣的关联，并估计患病率比（PR）及其各自的95%置信区间（95%CI）。
我们在分析中纳入了442名平均年龄为73±6.9岁的老年人；63.1%（n = 279）为女性，79.9%（n = 353）未受过教育或小学未毕业。50.9%（n = 225）的参与者有抑郁症状，49.8%（n = 220）有残疾。调整后的泊松回归模型显示，抑郁症状增加了高原地区老年人残疾的可能性（调整后的PR = 1.67；95%CI：1.34 - 2.08；p < 0.001）。
抑郁症状与高原地区老年人更高的残疾可能性相关。需要进行纵向研究，以便更好地了解高原人群中的这种关联，并及时进行干预，以减少这两种老年综合征的影响。
