Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.
Texas Children's Cancer and Hematology Centers, Texas Children's Hospital, Houston, Texas, USA.
Pediatr Blood Cancer. 2021 Dec;68(12):e29327. doi: 10.1002/pbc.29327. Epub 2021 Sep 14.
Liposarcoma is arare soft tissue sarcoma in children. While prognosis, clinical behavior, and response to therapy among the various histologic subtypes are well described in adults, data in children are limited. Here, we describe our experience treating 14 children with liposarcoma at a large, academic pediatric center and review the available pediatric literature. This comprehensive report adds treatment, survival, and genomic data to pediatric liposarcoma literature.
脂肪肉瘤是一种罕见的儿童软组织肉瘤。虽然成人中各种组织学亚型的预后、临床行为和对治疗的反应已有很好的描述,但儿童的数据有限。在这里,我们描述了在一家大型学术儿科中心治疗 14 名脂肪肉瘤患儿的经验,并回顾了现有的儿科文献。这份全面的报告为儿科脂肪肉瘤文献增加了治疗、生存和基因组数据。