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一名11岁患者的黏液样脂肪肉瘤。

Myxoid liposarcoma in an 11-year-old patient.

作者信息

Matsunobu Tomoya, Maekawa Akira, Inaba Yuna, Makihara Kosuke, Hisaoka Masanori, Iwamoto Yukihide

机构信息

Department of Orthopaedic Surgery, Kyushu Rosai Hospital, 1-1 Sonekitamachi, Kokura Minami-Ku, Kitakyushu, Fukuoka 800-0296 Japan.

Department of Surgical Pathology, Kyushu Rosai Hospital, Fukuoka Kitakyushu, Japan.

出版信息

Int Cancer Conf J. 2023 May 9;12(4):233-240. doi: 10.1007/s13691-023-00615-9. eCollection 2023 Oct.

Abstract

Myxoid liposarcoma is a mesenchymal malignancy that most commonly presents in young adults, with peak incidence between the ages of 30-50 years. The clinical behavior of myxoid liposarcoma has been well characterized in adults. However, little is known about the clinical features and treatment outcomes of myxoid liposarcoma in child, owing to its rarity. This case report describes an 11-year-old previously healthy female who presented with a painless mass in her right thigh. Ultrasonography, computed tomography, and magnetic resonance imaging demonstrated a soft tissue mass with clear margins in the subfascial plane superficial to the gracilis and sartorius muscles. She was diagnosed with myxoid liposarcoma based on histological and molecular cytogenetic examinations of the core-needle biopsy specimen. The patient subsequently underwent wide resection without any adjuvant treatment. The patient has not experienced any symptoms of local recurrence and metastases as of 2.5 years after surgery.

摘要

黏液样脂肪肉瘤是一种间叶组织恶性肿瘤,最常见于年轻人,发病高峰年龄在30至50岁之间。黏液样脂肪肉瘤在成人中的临床行为已得到充分描述。然而,由于其罕见性,关于儿童黏液样脂肪肉瘤的临床特征和治疗结果知之甚少。本病例报告描述了一名11岁的既往健康女性,她因右大腿出现无痛性肿块就诊。超声、计算机断层扫描和磁共振成像显示在股薄肌和缝匠肌浅面的筋膜下平面有一个边界清晰的软组织肿块。根据粗针活检标本的组织学和分子细胞遗传学检查,她被诊断为黏液样脂肪肉瘤。患者随后接受了广泛切除,未进行任何辅助治疗。截至术后2.5年,患者未出现任何局部复发和转移症状。

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本文引用的文献

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Pediatric liposarcoma: A case series and literature review.小儿脂肪肉瘤:病例系列与文献复习。
Pediatr Blood Cancer. 2021 Dec;68(12):e29327. doi: 10.1002/pbc.29327. Epub 2021 Sep 14.
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F-FDG PET/CT imaging features of lipomatous tumors.脂肪瘤性肿瘤的F-FDG PET/CT成像特征。
Am J Nucl Med Mol Imaging. 2020 Feb 25;10(1):74-82. eCollection 2020.

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