IEEE Trans Nanobioscience. 2022 Jan;21(1):3-9. doi: 10.1109/TNB.2021.3112539. Epub 2021 Dec 30.
In this work, CuO nanoparticles (NPs) decorated zinc oxide nanorods (ZnO NRs) on fluorine-doped tin oxide (FTO) substrate has been used as a working electrode. This working electrode has been used as an extended gate for field-effect transistor. The main objective is to use the EGFET (extended gate field effect transistor) as a glucose sensor. The proposed glucose sensor has good sensitivity of 6.643 mV/mM with a wide range of linearity (1mM-8mM) which covers the glucose level of human blood ranging from 4.4 mM to 6.6 mM. This novel concept of the glucose sensing using CuO NPs decorated ZnO nanorods based EGFET may be explored for sensing other saccharides such as mannose, fructose, and sucrose. This vertically grown ZnO nanorods decorated with CuO NPs based electrode gives reliable selectivity, good repeatability, and more stability. The performance of proposed sensor is also compared with commercially available glucose sensors. The sensitivity performance of the glucose sensor also confirms the capability to detect the glucose level from human blood and serum.
在这项工作中，在掺氟氧化锡（FTO）基底上使用氧化铜纳米粒子（NPs）修饰的氧化锌纳米棒（ZnO NRs）作为工作电极。该工作电极被用作场效应晶体管的扩展栅极。主要目的是将 EGFET（扩展栅场效应晶体管）用作葡萄糖传感器。所提出的葡萄糖传感器具有良好的灵敏度为 6.643 mV/mM 和较宽的线性范围（1mM-8mM），涵盖了人血液中葡萄糖水平范围从 4.4 mM 到 6.6 mM。这种使用基于 CuO NPs 修饰 ZnO 纳米棒的 EGFET 进行葡萄糖传感的新概念可以探索用于感测其他糖，如甘露糖、果糖和蔗糖。基于这种垂直生长的 ZnO 纳米棒和 CuO NPs 修饰的电极具有可靠的选择性、良好的重复性和更高的稳定性。还将所提出的传感器的性能与市售的葡萄糖传感器进行了比较。葡萄糖传感器的灵敏度性能也证实了从人血液和血清中检测葡萄糖水平的能力。
