Department of Neonatology, Bharati Vidyapeeth University, Pune, Maharashtra, India.
Bharati Vidyapeeth University, Pune, Maharashtra, India
BMJ Case Rep. 2021 Sep 14;14(9):e246100. doi: 10.1136/bcr-2021-246100.
Most reports of COVID-19 in neonates suggest that they are infected postnatally and present with gastrointestinal or respiratory symptoms. We describe a neonate who had community-acquired COVID-19, and presented with late-onset sepsis and developed dyselectrolytemia. The 26-day-old male baby had fever, feed refusal and shock. Rapid antigen test for SARS-CoV-2 by nasopharyngeal swab was positive and levels of circulating inflammatory markers were high. The baby was supported with antibiotics, and inotropic and vasopressor drugs. He had seizures and bradycardia due to dyselectrolytemia on day 2 of admission. On day 3, he had respiratory distress, with non-specific chest radiographic findings, and was managed with non-invasive support for 24 hours. The baby was discharged after 8 days. On serial follow-up, he was breastfeeding well and gaining weight appropriately with no morbidity. Our report highlights a unique presentation of COVID-19, with late-onset infection and shock-like features along with dyselectrolytemia and seizures.
大多数关于新生儿 COVID-19 的报告表明，他们是在出生后感染的，表现为胃肠道或呼吸道症状。我们描述了一名患有社区获得性 COVID-19 的新生儿，表现为晚发性败血症，并出现电解质紊乱。这名 26 天大的男婴出现发热、拒食和休克。鼻咽拭子快速抗原检测 SARS-CoV-2 呈阳性，循环炎症标志物水平升高。婴儿接受了抗生素、正性肌力和血管加压药物支持。入院第 2 天，他因电解质紊乱出现癫痫发作和心动过缓。入院第 3 天，他出现呼吸窘迫，胸部 X 线片无特异性发现，接受了 24 小时无创支持治疗。婴儿在 8 天后出院。在连续随访中，他的母乳喂养情况良好，体重增加正常，没有发病。我们的报告强调了 COVID-19 的一种独特表现，即晚发性感染和类似休克的特征，同时伴有电解质紊乱和癫痫发作。
