Bhan Kavyansh, Patel Ronak, Hasan Kamrul, Pimplé Mahesh, Sharma Sucheta, Nandwana Varsha, Basta Mhafrin
Trauma & Orthopaedics, Barts Health NHS Trust, London, GBR.
Orthopaedic Surgery, Punjab Institute of Medical Sciences, Jalandhar, IND.
Cureus. 2021 Aug 10;13(8):e17067. doi: 10.7759/cureus.17067. eCollection 2021 Aug.
The incidence of nonunion of fractures has been steadily rising owing to improved life expectancy following severe injuries along with rising cases of polytrauma. Once a nonunion is established, the chances of spontaneous healing are deemed to be quite low. Fracture nonunion continues to be a challenge in clinical practice with nonunions having a considerable impact on patient's quality of life causing both functional and psychosocial disability. Low-Intensity Pulsed Ultrasound (LIPUS) therapy is being projected as a viable and non-interventional alternative to surgical management of nonunions and delayed unions. LIPUS therapy is being widely recommended as a standalone treatment option for the treatment of established nonunions and delayed unions as it is believed to promote healing in all phases of fracture healing viz., inflammatory, intramembranous ossification, chondrogenesis, endochondral ossification and remodelling. In the current scenario of varying results and unclear clinical role of LIPUS therapy, we present a prospective case series of fracture nonunions and delayed unions treated with LIPUS therapy at a large District General Hospital.
由于严重创伤后预期寿命的提高以及多发伤病例的增加，骨折不愈合的发生率一直在稳步上升。一旦形成骨折不愈合，自发愈合的可能性被认为相当低。骨折不愈合在临床实践中仍然是一个挑战，骨折不愈合对患者的生活质量有相当大的影响，会导致功能和心理社会残疾。低强度脉冲超声（LIPUS）治疗被视为一种可行的、非介入性的替代方法，用于治疗骨折不愈合和延迟愈合。LIPUS治疗被广泛推荐为治疗已确诊的骨折不愈合和延迟愈合的独立治疗选择，因为人们认为它能促进骨折愈合的各个阶段，即炎症期、膜内成骨、软骨形成、软骨内成骨和重塑期的愈合。在目前LIPUS治疗结果各异且临床作用尚不清楚的情况下，我们在一家大型区综合医院展示了一组接受LIPUS治疗的骨折不愈合和延迟愈合的前瞻性病例系列。
