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一名患有播散性球孢子菌病罕见表现的老年男性。

An older male with an unusual presentation of disseminated coccidioidomycosis.

作者信息

Lokant Matthew S, Juskowich Joy J, Lee Shu Xian, Sarwari Arif R

机构信息

West Virginia University Department of Medicine, Department of Medicine, P.O. Box 9168, Morgantown, WV 26506, United States of America.

West Virginia University Department of Medicine, Sections of Hospital Medicine and Infectious Diseases, Department of Medicine, P.O. Box 9160, Morgantown, WV 26506, United States of America.

出版信息

IDCases. 2021 Aug 31;26:e01268. doi: 10.1016/j.idcr.2021.e01268. eCollection 2021.

DOI:10.1016/j.idcr.2021.e01268
PMID:34522611
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8426516/
Abstract

Coccidioidomycosis is a fungal disease endemic to the southwestern United States and other areas in the Western Hemisphere. Infection is usually acquired through inhalation. While infection is most often asymptomatic, early respiratory illness and infrequently extrapulmonary dissemination may occur. Immunocompromised individuals, particularly those with impaired cell-mediated immunity, are at greatest risk for dissemination. We present an atypical case of disseminated coccidioidomycosis in an immunocompetent male manifesting as peritoneal disease diagnosed during elective inguinal herniorrhaphy.

摘要

球孢子菌病是一种在美国西南部和西半球其他地区流行的真菌病。感染通常通过吸入获得。虽然感染大多无症状,但可能会出现早期呼吸道疾病,肺外播散则较为罕见。免疫功能低下的个体,尤其是细胞介导免疫受损者,发生播散的风险最高。我们报告一例免疫功能正常男性的播散性球孢子菌病非典型病例,表现为在择期腹股沟疝修补术中诊断出的腹膜疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d051/8426516/f532ac99f6e6/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d051/8426516/6d8b45ae4cf8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d051/8426516/c1d9cfd945d8/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d051/8426516/f532ac99f6e6/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d051/8426516/6d8b45ae4cf8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d051/8426516/c1d9cfd945d8/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d051/8426516/f532ac99f6e6/gr3.jpg

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本文引用的文献

1
Update on the Epidemiology of coccidioidomycosis in the United States.美国球孢子菌病流行病学最新情况
Med Mycol. 2019 Feb 1;57(Supplement_1):S30-S40. doi: 10.1093/mmy/myy095.
2
2016 Infectious Diseases Society of America (IDSA) Clinical Practice Guideline for the Treatment of Coccidioidomycosis.2016 年美国传染病学会(IDSA)关于球孢子菌病治疗的临床实践指南。
Clin Infect Dis. 2016 Sep 15;63(6):e112-46. doi: 10.1093/cid/ciw360. Epub 2016 Jul 27.
3
Peritoneal Coccidioidomycosis: a Rare Case Report and Review of the Literature.
腹膜腔球虫病:一例罕见病例报告及文献复习。
J Gastrointestin Liver Dis. 2015 Dec;24(4):527-30. doi: 10.15403/jgld.2014.1121.244.coc.
4
Recent advances in our understanding of the environmental, epidemiological, immunological, and clinical dimensions of coccidioidomycosis.近年来,我们对球孢子菌病的环境、流行病学、免疫学和临床方面的认识取得了进展。
Clin Microbiol Rev. 2013 Jul;26(3):505-25. doi: 10.1128/CMR.00005-13.
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Coccidioidal meningitis: update on epidemiology, clinical features, diagnosis, and management.球孢子菌性脑膜炎:流行病学、临床特征、诊断和治疗的最新进展。
Curr Infect Dis Rep. 2009 Jul;11(4):289-95. doi: 10.1007/s11908-009-0043-1.
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Initial presentation of coccidioidomycosis during inguinal herniorrhaphy.腹股沟疝修补术中球孢子菌病的初次表现。
Hernia. 2003 Jun;7(2):92-4. doi: 10.1007/s10029-002-0100-2. Epub 2003 Mar 15.
7
Peritoneal coccidioidomycosis: case report and review.
Clin Infect Dis. 2000 Jun;30(6):971-6. doi: 10.1086/313808.
8
Peritoneal coccidioidomycosis diagnosed incidentally at herniorrhaphy.疝修补术中偶然诊断出的腹膜球孢子菌病。
West J Med. 1993 Apr;158(4):406.