Massachusetts General Hospital, Mucosal Immunology and Biology Research Center, Boston, MA, USA.
Harvard Medical School, Boston, MA, USA.
Med. 2021 Sep 10;2(9):993-995. doi: 10.1016/j.medj.2021.08.008.
Multisystem inflammatory syndrome in children (MIS-C) is a severe, life-threatening, post-COVID-19 hyperinflammatory illness that is not yet fully understood. In this issue of , de Cevins et al. used a multi-parametric approach to define COVID-19-related disease, specifically identifying a molecular signature of the most severe form of COVID-19-related illness: MIS-C with myocarditis..
儿童多系统炎症综合征(MIS-C)是一种严重的、危及生命的 COVID-19 后过度炎症性疾病,目前尚未完全了解。在本期《柳叶刀》中,de Cevins 等人采用多参数方法定义 COVID-19 相关疾病,特别是确定了 COVID-19 相关疾病最严重形式:伴有心肌炎的 MIS-C 的分子特征。