Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina, USA.
LLC, Mt. Pleasant, South Carolina, USA.
Eur Eat Disord Rev. 2021 Nov;29(6):910-923. doi: 10.1002/erv.2864. Epub 2021 Sep 14.
Past traumatic events, subsequent posttraumatic stress disorder (PTSD) and related psychiatric comorbidities are commonly associated with eating disorders (EDs) in adults but remain understudied in adolescents.
Adolescent participants (mean [SD] age = 15.1 ± 1.5 years, 96.5% female) with EDs entering residential treatment (n = 647) at six sites in the United States completed validated self-report assessments of ED, PTSD, major depression, anxiety disorders and quality of life. Provisional DSM-5 PTSD diagnoses (PTSD+) were made via the Childhood Trauma Questionnaire, admission interviews and the PTSD Symptom Checklist for DSM-5.
PTSD+ occurred in 35.4% of participants, and those with ED-PTSD+ had significantly higher scores on all assessments (p ≤ 0.001), including measures of ED psychopathology, major depression, anxiety disorders and quality of life, as well as significantly higher rates of all forms of childhood trauma. Those with PTSD+ also exhibited a significantly higher percent median body mass index for age and sex and a lower propensity toward anorexia nervosa, restricting type.
Results confirm that adolescent patients in residential treatment with ED-PTSD+ are more symptomatic and have worse quality of life than their ED counterparts without PTSD. Integrated treatment approaches that effectively address ED-PTSD+ are greatly needed in ED programs that treat adolescents.
过去的创伤事件、随后的创伤后应激障碍(PTSD)和相关的精神共病在成年人中常与饮食障碍(ED)相关,但在青少年中研究较少。
美国六个地点接受住院治疗的 ED 青少年参与者(平均[SD]年龄=15.1±1.5 岁,96.5%为女性)完成了 ED、PTSD、重度抑郁症、焦虑障碍和生活质量的经过验证的自我报告评估。通过童年创伤问卷、入院访谈和 DSM-5 创伤后应激障碍症状清单,对暂定的 DSM-5 PTSD 诊断(PTSD+)进行了评估。
35.4%的参与者患有 PTSD+,ED-PTSD+患者在所有评估(p≤0.001)中得分显著更高,包括 ED 精神病理学、重度抑郁症、焦虑障碍和生活质量的测量,以及所有形式的童年创伤的发生率也显著更高。PTSD+患者的中位数体质指数年龄和性别也显著更高,且厌食症倾向较低。
结果证实,与没有 PTSD 的 ED 患者相比,住院治疗的 ED-PTSD+青少年患者症状更严重,生活质量更差。在治疗青少年的 ED 项目中,非常需要有效的 ED-PTSD+综合治疗方法。