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儿童期起病的饮食障碍与更高的创伤剂量、临时性创伤后应激障碍以及住院治疗中的疾病严重程度相关。

Eating disorder onset during childhood is associated with higher trauma dose, provisional PTSD, and severity of illness in residential treatment.

机构信息

Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina, USA.

Timothy D. Brewerton, MD, LLC, Mt. Pleasant, South Carolina, USA.

出版信息

Eur Eat Disord Rev. 2022 May;30(3):267-277. doi: 10.1002/erv.2892. Epub 2022 Feb 24.

Abstract

OBJECTIVE

Age of eating disorder (ED) onset has been of significant interest to both researchers and clinicians. The identification of factors associated with early or child onset has important prevention and treatment implications. The presence of prior trauma, resultant posttraumatic stress disorder (PTSD), ED severity, and comorbid psychopathology are of particular relevance to age of ED onset, but data are limited.

METHODS

Adults (≥18 years, 93% female, total n = 1283) admitted to residential ED treatment self-reported age of ED onset. Patients were divided into child onset (ages 5-10 years), adolescent onset (11-17 years), and adult onset (≥18 years) groups and compared on a number of clinical features and assessment measures.

RESULTS

The child onset group had significantly higher rates and doses of traumatic life events; higher current PTSD prevalence; higher BMIs, higher severity of ED, depression and state-trait anxiety symptoms; worse quality of life; and more prior inpatient and residential admissions for ED treatment, in comparison to both the adolescent and adult onset groups. Similarly, the adolescent onset group had significantly higher rates than the adult onset group.

CONCLUSIONS

These results have important implications for prevention, treatment and long-term follow-up and highlight the need for early trauma-focussed treatment of ED patients.

摘要

目的

饮食失调(ED)发病年龄一直是研究人员和临床医生关注的焦点。确定与早期或儿童发病相关的因素对预防和治疗具有重要意义。先前存在创伤、由此产生的创伤后应激障碍(PTSD)、ED 严重程度和合并的精神病理学与 ED 发病年龄特别相关,但数据有限。

方法

接受住院 ED 治疗的成年人(≥18 岁,93%为女性,总 n=1283)自我报告 ED 发病年龄。患者分为儿童发病(年龄 5-10 岁)、青少年发病(11-17 岁)和成人发病(≥18 岁)组,并在多个临床特征和评估措施上进行比较。

结果

与青少年和成年发病组相比,儿童发病组的创伤性生活事件发生率和剂量更高;当前 PTSD 患病率更高;BMI 更高、ED 严重程度、抑郁和状态特质焦虑症状更严重;生活质量更差;ED 治疗的住院和住院入院次数更多。同样,青少年发病组的发生率也显著高于成年发病组。

结论

这些结果对预防、治疗和长期随访具有重要意义,强调需要对 ED 患者进行早期以创伤为重点的治疗。

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