Department of Chemistry, University of California, Riverside, California 92521, USA.
Org Biomol Chem. 2021 Sep 15;19(35):7535-7543. doi: 10.1039/d1ob00812a.
This mini-review provides a concise overview of the biosynthetic pathway and pharmacology of bisbenzylisoquinoline alkaloid (bisBIA) natural products. Additional emphasis is given to the methodologies in the total syntheses of both simpler acyclic diaryl ether dimers and their macrocyclic counterparts bearing two diaryl ether linkages.
这篇迷你综述简要概述了双苄基异喹啉生物碱（bisBIA）天然产物的生物合成途径和药理学。此外，本文还重点介绍了简单无环二芳基醚二聚体及其具有两个二芳基醚键的大环类似物的全合成方法。
