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急性后极部多灶性鳞状色素上皮病变

Acute posterior multifocal placoid pigment epitheliopathy (APMPPE).

作者信息

Testi Ilaria, Vermeirsch Sandra, Pavesio Carlos

机构信息

Department of Uveitis, Moorfields Eye Hospital, National Health Service Foundation Trust, 162 City Rd, Old Street, London, EC1V 2PD, UK.

出版信息

J Ophthalmic Inflamm Infect. 2021 Nov 1;11(1):31. doi: 10.1186/s12348-021-00263-1.

DOI:10.1186/s12348-021-00263-1
PMID:34524577
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8443720/
Abstract

BACKGROUND

Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is a rare inflammatory eye disease, affecting the inner choroid and the outer retina. Recent advances in multimodal imaging have been important in the understanding of the pathophysiology of the disease, allowing a better characterization of the morphology of this condition.

METHODS

Narrative review.

RESULTS

In this review, a comprehensive overview of clinical features, imaging findings, treatment management, and long-term outcomes of patients with APMPPE will be provided.

CONCLUSIONS

Although APMPPE was originally believed to be a self-limited condition with a good prognosis, the disease can be recurrent and result in significant loss of vision function. Fundus imaging plays an important role in the diagnosis and management of the disease, allowing to evaluate response to treatment and onset of complications.

摘要

背景

急性后极部多灶性鳞状色素上皮病变(APMPPE)是一种罕见的炎症性眼病,累及脉络膜内层和视网膜外层。多模态成像的最新进展对理解该疾病的病理生理学具有重要意义,有助于更好地描述这种疾病的形态特征。

方法

叙述性综述。

结果

在本综述中,将全面概述APMPPE患者的临床特征、影像学表现、治疗管理及长期预后。

结论

尽管APMPPE最初被认为是一种预后良好的自限性疾病,但该疾病可能会复发,并导致视力功能严重丧失。眼底成像在该疾病的诊断和管理中起着重要作用,有助于评估治疗反应和并发症的发生情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/8443720/00008fe3caf3/12348_2021_263_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/8443720/c38e5341bc7d/12348_2021_263_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/8443720/66b2ff8c7aa4/12348_2021_263_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/8443720/00008fe3caf3/12348_2021_263_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/8443720/c38e5341bc7d/12348_2021_263_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/8443720/66b2ff8c7aa4/12348_2021_263_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/8443720/00008fe3caf3/12348_2021_263_Fig3_HTML.jpg

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