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门诊全膝关节置换术患者行椎管内麻醉与全身麻醉的效果比较:一项基于全国倾向评分匹配分析的早期术后结局研究。

Spinal versus general anesthesia for patients undergoing outpatient total knee arthroplasty: a national propensity matched analysis of early postoperative outcomes.

机构信息

Department of Anesthesiology, The Warren Alpert Medical School of Brown University, 593 Eddy Street, Davol #129, Providence, RI, 02903, USA.

Department of Anesthesiology, Rhode Island Hospital, Providence, RI, USA.

出版信息

BMC Anesthesiol. 2021 Sep 15;21(1):226. doi: 10.1186/s12871-021-01442-2.

Abstract

BACKGROUND

A comparison of different anesthetic techniques to evaluate short term outcomes has yet to be performed for patients undergoing outpatient knee replacements. The aim of this investigation was to compare short term outcomes of spinal (SA) versus general anesthesia (GA) in patients undergoing outpatient total knee replacements.

METHODS

The ACS NSQIP datasets were queried to extract patients who underwent primary, elective, unilateral total knee arthroplasty (TKA) between 2005 and 2018 performed as an outpatient procedure. The primary outcome was a composite score of serious adverse events (SAE). The primary independent variable was the type of anesthesia (e.g., general vs. spinal).

RESULTS

A total of 353,970 patients who underwent TKA procedures were identified comprising of 6,339 primary, elective outpatient TKA procedures. Of these, 2,034 patients received GA and 3,540 received SA. A cohort of 1,962 patients who underwent outpatient TKA under GA were propensity matched for covariates with patients who underwent outpatient TKA under SA. SAE rates at 72 h after surgery were not greater in patients receiving GA compared to SA (0.92%, 0.66%, P = 0.369). In contrast, minor adverse events were greater in the GA group compared to SA (2.09%, 0.51%), P < 0.001. The rate of postoperative transfusion was greater in the patients receiving GA.

CONCLUSIONS

The type of anesthetic technique, general or spinal anesthesia does not alter short term SAEs, readmissions and failure to rescue in patients undergoing outpatient TKR surgery. Recognizing the benefits of SA tailored to the anesthetic management may maximize the clinical benefits in this patient population.

摘要

背景

对于接受门诊膝关节置换术的患者,尚未对不同麻醉技术进行比较以评估短期结果。本研究旨在比较行门诊全膝关节置换术的患者接受椎管内麻醉(SA)与全身麻醉(GA)的短期结果。

方法

从 ACS NSQIP 数据库中提取 2005 年至 2018 年间接受单侧初次、择期全膝关节置换术(TKA)且作为门诊手术的患者。主要结局是严重不良事件(SAE)的综合评分。主要的独立变量是麻醉类型(如全身麻醉与椎管内麻醉)。

结果

共确定了 353970 例接受 TKA 手术的患者,其中包括 6339 例初次、择期门诊 TKA 手术。其中 2034 例患者接受 GA,3540 例接受 SA。对接受 GA 行门诊 TKA 的 1962 例患者进行协变量的倾向匹配,与接受 SA 行门诊 TKA 的患者进行比较。与接受 SA 的患者相比,接受 GA 的患者术后 72 小时的 SAE 发生率没有增加(0.92%,0.66%,P=0.369)。相反,GA 组的轻微不良事件发生率高于 SA 组(2.09%,0.51%),P<0.001。接受 GA 的患者术后输血率更高。

结论

在接受门诊 TKR 手术的患者中,麻醉技术的类型(全身麻醉或椎管内麻醉)不会改变短期 SAE、再入院率和抢救失败。认识到 SA 的优势并根据麻醉管理进行个体化,可以使该患者人群获得最大的临床获益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2158/8442468/f9493590a286/12871_2021_1442_Fig1_HTML.jpg

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