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饮茶与血压进展及高血压发病率的关联。

Associations of tea consumption with blood pressure progression and hypertension incidence.

作者信息

Niu Xiao-Ge, Cai Can, Liu Fang-Chao, Li Jian-Xin, Huang Ke-Yong, Yang Xue-Li, Cao Jie, Chen Shu-Feng, Li Hong-Fan, Shen Chong, Zhao Ying-Xin, Hu Dong-Sheng, Gu Shu-Jun, Huang Jian-Feng, Lu Xiang-Feng, Gu Dong-Feng

机构信息

Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Tianjin Key Laboratory of Environment, Nutrition and Public Health, Department of Occupational and Environmental Health, School of Public Health, Tianjin Medical University, Tianjin, China.

出版信息

J Geriatr Cardiol. 2021 Aug 28;18(8):645-653. doi: 10.11909/j.issn.1671-5411.2021.08.004.

Abstract

BACKGROUND

Association between tea consumption and incident hypertension remains uncertain. This study conducted to examine the health effects of tea consumption on blood pressure progression and hypertension incidence.

METHODS

A population-based cohort of 38,913 Chinese participants without hypertension at baseline were included in the current study. Information on tea consumption was collected through standardized questionnaires. Associations of tea consumption with blood pressure progression and incident hypertension were analyzed using logistic regression models and Cox proportional hazards regression models, respectively.

RESULTS

During a median follow-up of 5.9 years, 17,657 individuals had experienced progression to a higher blood pressure stage and 5,935 individuals had developed hypertension. In multivariate analyses, habitual tea drinkers (≥ 3 times/week for at least six months) had a 17% lower risk for blood pressure progression [odds ratio (OR) = 0.83, 95% CI: 0.79-0.88] and a 14% decreased risk for incident hypertension [hazard ratio (HR) = 0.86, 95% CI: 0.80-0.91] compared with non-habitual tea drinkers. Individuals in different baseline blood pressure groups could obtain similar benefit from habitual tea drinking. In terms of tea consumption amount, an inverse, linear dose-response relation between monthly consumption of tea leaves and risk of blood pressure progression was observed, while the risk of incident hypertension did not reduce further after consuming around 100 g of tea leaves per month.

CONCLUSIONS

Our study demonstrated that habitual tea consumption could provide preventive effect against blood pressure progression and hypertension incidence.

摘要

背景

饮茶与高血压发病之间的关联仍不明确。本研究旨在探讨饮茶对血压进展和高血压发病率的健康影响。

方法

本研究纳入了38913名基线时无高血压的中国人群队列。通过标准化问卷收集饮茶信息。分别使用逻辑回归模型和Cox比例风险回归模型分析饮茶与血压进展和高血压发病之间的关联。

结果

在中位随访5.9年期间,17657人经历了血压进展至更高阶段,5935人患上了高血压。在多变量分析中,与非习惯性饮茶者相比,习惯性饮茶者(每周≥3次,至少持续6个月)血压进展风险降低17%[比值比(OR)=0.83,95%置信区间(CI):0.79-0.88],高血压发病风险降低14%[风险比(HR)=0.86,95%CI:0.80-0.91]。不同基线血压组的个体均可从习惯性饮茶中获得类似益处。就饮茶量而言,观察到每月茶叶消费量与血压进展风险之间存在反向线性剂量反应关系,而每月饮用约100克茶叶后,高血压发病风险并未进一步降低。

结论

我们的研究表明,习惯性饮茶可预防血压进展和高血压发病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2986/8390932/80d47c6e5bf2/jgc-18-8-645-1.jpg

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