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与稳定型下消化道出血患者急诊科出院、结局及随访率相关的因素

Factors Associated With Emergency Department Discharge, Outcomes and Follow-Up Rates of Stable Patients With Lower Gastrointestinal Bleeding.

作者信息

Martin Tracey A, Tewani Sunena, Clarke Lindsay, Aboubakr Aiya, Palanisamy Srikanth, Lee Jihui, Crawford Carl V, Wan David W

机构信息

Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, NY, USA.

Division of Hospital Medicine, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, NY, USA.

出版信息

Gastroenterology Res. 2021 Aug;14(4):227-236. doi: 10.14740/gr1425. Epub 2021 Jul 28.

Abstract

BACKGROUND

Lower gastrointestinal bleeding (LGIB) is a common reason for hospitalization. However, recent data suggest low-risk patients may be safely evaluated as an outpatient. Here, we compare stable LGIB patients discharged from the emergency department (ED) with those admitted, determine factors associated with discharge and 30-day outcomes, and evaluate follow-up rates amongst the discharged cohort.

METHODS

A retrospective study of stable LGIB patients (heart rate < 100 beats/min, systolic blood pressure > 100 mm Hg and blood on rectal exam) who presented to the ED was conducted. Factors associated with discharge and rates of outpatient follow-up were determined in the discharged cohort. Therapeutic interventions and 30-day outcomes (including re-bleeding, re-admission and mortality rates) were compared between the admitted and discharged groups.

RESULTS

Ninety-seven stable LGIB patients were reviewed, of whom 38% were discharged and characteristics associated with discharge included age (P < 0.001), lack of aspirin (P < 0.002) and anticoagulant (P < 0.004) use, higher index hemoglobin (P < 0.001) and albumin (P < 0.001), lower blood urea nitrogen (P < 0.001) and creatinine (P = 0.008), lower Oakland score (P < 0.001), lower Charlson Comorbidity Index (P < 0.001) and lack of transfusion requirements (P < 0.001). There was no statistical difference in 30-day re-bleeding, re-admission or mortality rates between admitted and discharged patients. Discharged patients had a 46% outpatient follow-up rate.

CONCLUSIONS

While early discharge in low-risk LGIB patients appears to be safe and associated with a decrease in length of stay, further studies are needed to guide timely and appropriate outpatient evaluation.

摘要

背景

下消化道出血(LGIB)是住院的常见原因。然而,近期数据表明,低风险患者可作为门诊患者进行安全评估。在此,我们比较了从急诊科(ED)出院的稳定型LGIB患者与住院患者,确定与出院及30天结局相关的因素,并评估出院队列中的随访率。

方法

对就诊于ED的稳定型LGIB患者(心率<100次/分钟、收缩压>100 mmHg且直肠检查有血)进行回顾性研究。在出院队列中确定与出院及门诊随访率相关的因素。比较住院组和出院组的治疗干预措施及30天结局(包括再出血、再入院和死亡率)。

结果

对97例稳定型LGIB患者进行了评估,其中38%出院,与出院相关的特征包括年龄(P<0.001)、未使用阿司匹林(P<0.002)和抗凝剂(P<0.004)、较高的初始血红蛋白(P<0.001)和白蛋白(P<0.001)、较低的血尿素氮(P<0.001)和肌酐(P=0.008)、较低的奥克兰评分(P<0.001)、较低的Charlson合并症指数(P<0.001)以及无需输血(P<0.001)。住院患者和出院患者在30天再出血、再入院或死亡率方面无统计学差异。出院患者的门诊随访率为46%。

结论

虽然低风险LGIB患者早期出院似乎是安全的,且与住院时间缩短相关,但仍需要进一步研究以指导及时、恰当的门诊评估。

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