Dedovets Dmytro, Li Qingyuan, Leclercq Loïc, Nardello-Rataj Veronique, Leng Jacques, Zhao Shuangliang, Pera-Titus Marc
Eco-Efficient Products and Processes Laboratory (E2P2L), UMI 3464 CNRS-Solvay, 3966 Jin Du Road, Xin Zhuang Ind Zone, 201108, Shanghai, China.
Laboratoire du Futur (LOF), UMR 5258, CNRS-Solvay-Universite Bordeaux 1, 178 Av Dr Albert Schweitzer, 33608, Pessac Cedex, France.
Angew Chem Int Ed Engl. 2022 Jan 21;61(4):e202107537. doi: 10.1002/anie.202107537. Epub 2021 Oct 1.
Pickering emulsions, foams, bubbles, and marbles are dispersions of two immiscible liquids or of a liquid and a gas stabilized by surface-active colloidal particles. These systems can be used for engineering liquid-liquid-solid and gas-liquid-solid microreactors for multiphase reactions. They constitute original platforms for reengineering multiphase reactors towards a higher degree of sustainability. This Review provides a systematic overview on the recent progress of liquid-liquid and gas-liquid dispersions stabilized by solid particles as microreactors for engineering eco-efficient reactions, with emphasis on biobased reagents. Physicochemical driving parameters, challenges, and strategies to (de)stabilize dispersions for product recovery/catalyst recycling are discussed. Advanced concepts such as cascade and continuous flow reactions, compartmentalization of incompatible reagents, and multiscale computational methods for accelerating particle discovery are also addressed.
皮克林乳液、泡沫、气泡和弹珠是由表面活性胶体颗粒稳定的两种互不相溶的液体或一种液体与一种气体的分散体系。这些体系可用于设计用于多相反应的液-液-固和气-液-固微反应器。它们构成了将多相反应器重新设计以实现更高可持续性的原始平台。本综述系统概述了以固体颗粒稳定的液-液和气-液分散体系作为用于设计生态高效反应的微反应器的最新进展，重点是生物基试剂。讨论了物理化学驱动参数、挑战以及用于产品回收/催化剂循环的（去）稳定分散体系的策略。还介绍了级联和连续流动反应、不相容试剂的分隔以及加速颗粒发现的多尺度计算方法等先进概念。
