School of Dentistry, Centro Universitário UniRuy Wyden, Av. Luis Viana Filho, 3230, Paralela Salvador, BA, Brazil.
Stomatologija. 2021;23(1):3-8.
Oral lesions has been reported in coronavirus disease 2019 (COVID-19). However, there are gaps about the occurrence. The aim of this study was to describe the clinical characteristics of oral lesions in patients with COVID-19.
A systematic review was conducted in four electronic databases (PubMed, Lilacs, Cochrane and Google Scholar) with the search terms: "coronavírus", "COVID-19", "SARS-CoV-2", "novel coronavírus", "2019nCoV", "oral manifestation", "mucosal lesions", "oral lesions", "mucosa viral lesions" and "oral conditions". Articles were limited to those published between january and july 2020, and in English.
Initially, 182 articles were found, after reading the titles and abstracts a total of 24 records were included for full-text reading. Finally, 22 articles were included for data extraction and assessement. We identified and subsequently discussed clinical characteristics and differential diagnosis.
The etiology of many oral mucosal lesions is intimately related to infectious, immunological, and psychosocial factors. Therefore, amid the SARS-CoV-2 pandemic in which many doubts about the disease still remain, caution is needed when evaluating patients and establishing correlations with other diseases that could be associated.
有报道称，2019 冠状病毒病（COVID-19）患者会出现口腔病变。然而，目前对此类病变的发生情况还存在一些认识上的空白。本研究旨在描述 COVID-19 患者口腔病变的临床特征。
我们在四个电子数据库（PubMed、Lilacs、Cochrane 和 Google Scholar）中检索了与“冠状病毒”“COVID-19”“SARS-CoV-2”“新型冠状病毒”“2019nCoV”“口腔表现”“黏膜病变”“口腔病变”“黏膜病毒病变”和“口腔状况”等相关的术语，并进行了系统性综述。文献检索的时间范围为 2020 年 1 月至 7 月，仅限英文文献。
最初，我们共找到了 182 篇文章，在阅读了标题和摘要之后，我们又对总共 24 篇文章进行了全文阅读。最终，我们纳入了 22 篇文章进行数据提取和评估。我们确定并随后讨论了口腔病变的临床特征和鉴别诊断。
许多口腔黏膜病变的病因都与感染、免疫和心理社会因素密切相关。因此，在 2019 冠状病毒病大流行期间，当我们评估患者并与可能相关的其他疾病建立关联时，需要谨慎。
