禽红细胞细胞核提取物对H5基因的特异性反式激活作用。
H5 gene specific trans-activation by nuclear extracts from avian erythroid cells.
作者信息
Wigley P L, Wells J R
机构信息
Department of Biochemistry, University of Adelaide, South Australia.
出版信息
Mol Cell Biol. 1987 Oct;7(10):3853-6. doi: 10.1128/mcb.7.10.3853-3856.1987.
Abstract
Nuclear extracts from chicken erythroid cells selectively stimulate transcription of the chicken histone H5 gene (and not of other chicken histone genes) after coinjection into frog oocytes. This effect is shown to involve an enhancerlike activity, and a region of the H5 gene sufficient to mediate trans-activation is defined.
摘要
将鸡红细胞的核提取物与蛙卵母细胞共注射后，能选择性地刺激鸡组蛋白H5基因（而非其他鸡组蛋白基因）的转录。这种效应显示涉及一种类似增强子的活性，并且确定了H5基因中足以介导反式激活的一个区域。
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