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天然抗氧化剂对γ射线诱导损伤的防护作用——综述

Protective rules of natural antioxidants against gamma-induced damage-A review.

作者信息

Jameel Qaswaa Y, Mohammed Nameer K

机构信息

Department of Food Science Colleges of Agricultural and Forestry Mosul University Mosul Iraq.

Department of Food Science College of Agriculture Tikrit University Tikrit Iraq.

出版信息

Food Sci Nutr. 2021 Jul 21;9(9):5263-5278. doi: 10.1002/fsn3.2469. eCollection 2021 Sep.

Abstract

Phytochemicals accessible in food have demonstrated efficiency against impairment by gamma radiation. The review presented here is an attempt to show the pharmacological outline of the activity of the natural antioxidants and its primary action of molecular mechanism against the damage induced by gamma rays. This research focused on the results of the in vitro dosage of natural antioxidants relationship, and on the correlation of this information with the statistical variables. Moreover, it deliberated the natural compounds which could decrease the unwelcome impacts of gamma radiation and safeguard biological systems from radiation-stimulated genotoxicity. The outcomes indicated that natural compounds can be utilized as an adjunct to orthodox radiotherapy and cultivate it as an effectual drug for the clinical administration of ailments.

摘要

食物中含有的植物化学物质已证明对γ辐射造成的损伤具有防护作用。本文献综述旨在阐述天然抗氧化剂活性的药理学概述及其针对γ射线所致损伤的分子机制的主要作用。本研究聚焦于天然抗氧化剂体外剂量关系的结果,以及该信息与统计变量的相关性。此外,还探讨了可减轻γ辐射不良影响并保护生物系统免受辐射诱发的基因毒性的天然化合物。结果表明,天然化合物可作为传统放射治疗的辅助手段,并将其开发成为治疗疾病的有效临床用药。

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