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2021 年 2 月至 3 月,荷兰,Cepheid Xpert MRSA NxG 检测对耐甲氧西林 的误判。

Misidentification of meticillin-resistant by the Cepheid Xpert MRSA NxG assay, the Netherlands, February to March 2021.

机构信息

University of Groningen, University Medical Center Groningen, Department of Medical Microbiology, Groningen, the Netherlands.

Isala Hospital, Laboratory for Medical Microbiology and Infectious Diseases, Zwolle, the Netherlands.

出版信息

Euro Surveill. 2021 Sep;26(37). doi: 10.2807/1560-7917.ES.2021.26.37.2100800.

Abstract

We describe two false-negative results in the detection of meticillin-resistant (MRSA) of sequence type 398 and type t011 using the Cepheid Xpert MRSA NxG assay. The isolates were recovered in late February and early March 2021 from two patients in different hospitals in the northern Netherlands. Variations between the two isolate genomes indicate that this MRSA strain might have been spreading for some time and could have disseminated to other regions of the Netherlands and other European countries.

摘要

我们描述了两例使用 Cepheid Xpert MRSA NxG 检测时对耐甲氧西林金黄色葡萄球菌(MRSA)序列型 398 和 t011 的假阴性结果。这两个分离株于 2021 年 2 月下旬和 3 月初从荷兰北部的两家不同医院的两名患者中分离得到。两个分离株基因组之间的差异表明,这种 MRSA 菌株可能已经传播了一段时间,并可能传播到荷兰的其他地区和其他欧洲国家。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c974/8447827/5471756ac505/2100800-f1.jpg

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