Central Institute of Science and Technology, Kathmandu, Nepal.
Madan Bhandari University of Science and Technology, Lalitpur, Nepal.
Chem Biodivers. 2021 Nov;18(11):e2100345. doi: 10.1002/cbdv.202100345. Epub 2021 Oct 13.
Medicinal plants, a source of different phytochemical compounds, are now subjected to a variety of environmental stresses during their growth and development. Different ecologically limiting factors including temperature, carbon dioxide, lighting, ozone, soil water, soil salinity and soil fertility has significant impact on medicinal plants' physiological and biochemical responses, as well as the secondary metabolic process. Secondary metabolites (SMs) are useful for assessing the quality of therapeutic ingredients and nowadays, these are used as important natural derived drugs such as immune suppressant, antibiotics, anti-diabetic, and anti-cancer. Plants have the ability to synthesize a variety of secondary metabolites to cope with the negative effects of stress. Here, we focus on how individual environmental variables influence the accumulation of plant secondary metabolites. A total of 48 articles were found to be relevant to the review topic during our systematic review. The review showed the influence of different environmental variables on SMs production and accumulation is complex suggesting the relationship are not only species-specific but also related to increases and decline in SMs by up to 50 %. Therefore, this review improves our understanding of plant SMs ability to adapt to key environmental factors. This can aid in the efficient and long-term optimization of cultivation techniques under ambient environmental conditions in order to maximize the quality and quantity of SMs in plants.
药用植物是不同植物化学化合物的来源，在生长和发育过程中会受到各种环境胁迫。包括温度、二氧化碳、光照、臭氧、土壤水分、土壤盐分和土壤肥力在内的不同生态限制因素，对药用植物的生理生化反应以及次生代谢过程有重大影响。次生代谢产物（SMs）可用于评估治疗成分的质量，如今被用作重要的天然衍生药物，如免疫抑制剂、抗生素、抗糖尿病药和抗癌药。植物有能力合成多种次生代谢产物以应对应激的负面影响。在这里，我们重点关注个别环境变量如何影响植物次生代谢产物的积累。在系统评价中，我们共发现 48 篇与综述主题相关的文章。综述表明，不同环境变量对 SMs 产生和积累的影响是复杂的，这表明这种关系不仅具有物种特异性，而且还与 SMs 的增加和减少多达 50%有关。因此，本综述增进了我们对植物 SMs 适应关键环境因素的能力的理解。这有助于在环境条件下高效和长期优化栽培技术，以最大限度地提高植物中 SMs 的质量和数量。
