Department of Respiratory Medicine, Shenzhen Children's Hospital, Shenzhen, Guangdong 518026, China (Yang Q, Email: 6468633@qq. com).
Zhongguo Dang Dai Er Ke Za Zhi. 2021;23(9):933-937. doi: 10.7499/j.issn.1008-8830.2104155.
To study the clinical features of obstructive sleep apnea (OSA) in children with obesity.
A retrospective analysis was performed on the medical data of 33 obese children aged 7-15 years, who were diagnosed with OSA and received polysomnography (PSG) in the Department of Respiratory Medicine in Shenzhen Children's Hospital. Fifty OSA children with normal body weight, matched for sex and age, were enrolled as the control group.
Among the 33 obese children with OSA, the three most common daytime symptoms were inattention in 30 children (91%), somnolence in 22 children (67%), and morning fatigue in 21 children (64%), and the three most common nocturnal symptoms were snoring in 27 children (82%), mouth breathing in 20 children (61%), and sweating in 16 children (49%). Compared with the reference values of normal children, both the OSA + obesity group and the control group had prolonged light sleep, shortened deep sleep, and a significantly shortened rapid eye movement (REM) period, while there was no significant difference in these indices between the two groups (>0.05). The apnea-hypopnea index, obstructive apnea/hypopnea index, and oxygen desaturation index in both REM and non-REM periods in the OSA +obesity group were significantly higher than those in the control group (<0.05), while the lowest blood oxygen saturation during sleep was significantly lower in the OSA + obesity group (<0.05).
The children with obesity and OSA have the main daytime symptoms of inattention, somnolence, and morning fatigue and the main nocturnal symptoms of snoring, mouth breathing, and sweating. There is no significant difference in sleep structure between OSA children with obesity and those with normal body weight; however, respiratory events and blood oxygen saturation decline are more severe in OSA children with obesity. .
研究肥胖儿童阻塞性睡眠呼吸暂停（OSA）的临床特征。
对在深圳市儿童医院呼吸科诊断为 OSA 并接受多导睡眠图（PSG）检查的 33 例 7-15 岁肥胖儿童的病历资料进行回顾性分析，选取同期性别、年龄匹配的 50 例体重正常的 OSA 儿童作为对照组。
33 例肥胖 OSA 患儿中，日间症状最常见的是注意力不集中 30 例（91%）、嗜睡 22 例（67%）和晨起疲劳 21 例（64%），夜间症状最常见的是打鼾 27 例（82%）、张口呼吸 20 例（61%）和出汗 16 例（49%）。与正常儿童参考值相比，OSA+肥胖组和对照组均存在轻睡眠时间延长、深睡眠时间缩短和快动眼（REM）期显著缩短，两组间上述指标差异无统计学意义（>0.05）。OSA+肥胖组 REM 期和非 REM 期的呼吸暂停低通气指数、阻塞性呼吸暂停低通气指数和氧减指数均明显高于对照组（<0.05），最低睡眠时血氧饱和度明显低于对照组（<0.05）。
肥胖合并 OSA 的患儿主要日间症状为注意力不集中、嗜睡和晨起疲劳，主要夜间症状为打鼾、张口呼吸和出汗。肥胖合并 OSA 患儿与体重正常的 OSA 患儿睡眠结构无明显差异，但肥胖合并 OSA 患儿呼吸事件和血氧饱和度下降更严重。
