Mayo Clinic Ambulance Service, Rochester, MN.
Mayo Clinic Ambulance Service, Rochester, MN.
Air Med J. 2021 Sep-Oct;40(5):322-324. doi: 10.1016/j.amj.2021.05.006. Epub 2021 Jun 12.
We evaluated a point-of-care prothrombin time (PT)/international normalized ratio (INR) cartridge-based analyzer for its feasibility, accuracy, and value in critical care air transport.
In this prospective study, blood samples from 10 randomly selected adult patients were tested with the cartridge during transport to determine feasibility. The cartridge results were compared with the laboratory results for the same samples. Similarly, blood samples from an additional 20 randomly selected adult patients were tested to determine test accuracy. A chart review identified 110 adult patients with PT/INR cartridge results to determine the clinical value of those results.
Data from the first group of 10 patients showed that vibration did not affect use of the cartridge. The average bias between the 2 testing methods was 0.0 INR units. A comparison of the PT/INR cartridge results and the laboratory results from the group of 20 patients showed that 73% of the cartridge values were within 0.2 of the laboratory values, 83% were within 0.4, and 93% were within 0.6. Of the 110 patients whose charts showed PT/INR cartridge results, 23% received blood products (45 trauma patients and 65 medical patients).
The PT/INR cartridge withstands the rigors of rotor wing transport and provides accurate, valuable results for making clinical decisions.
我们评估了一种即时凝血酶原时间（PT）/国际标准化比值（INR）检测卡式分析器在危重症航空转运中的可行性、准确性和价值。
在这项前瞻性研究中，对随机选择的 10 名成年患者的血液样本进行了检测，以确定检测卡的可行性。将检测卡的结果与同一批样本的实验室结果进行比较。同样，对另外 20 名随机选择的成年患者的血液样本进行了检测，以确定检测的准确性。通过病历回顾，确定了 110 名成年患者的 PT/INR 检测卡结果，以评估这些结果的临床价值。
第一组 10 名患者的数据显示，振动不会影响检测卡的使用。两种检测方法的平均偏差为 0.0 INR 单位。对 20 名患者的 PT/INR 检测卡结果和实验室结果进行比较后发现，73%的检测卡值与实验室值相差 0.2 以内，83%的检测卡值与实验室值相差 0.4 以内，93%的检测卡值与实验室值相差 0.6 以内。在有 PT/INR 检测卡结果的 110 名患者中，23%的患者接受了血液制品（45 名创伤患者和 65 名内科患者）。
PT/INR 检测卡能够承受直升机运输的严苛条件，并提供准确、有价值的结果，有助于临床决策。
