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患有血管性血友病的彭布罗克威尔士柯基犬完全闭塞的动脉导管未闭后晚期再通。

Late recanalization after complete occlusion of patent ductus arteriosus in a Pembroke Welsh Corgi with von Willebrand disease.

机构信息

Division of Cardiology, Matsubara Animal Hospital, Matsubara, Japan.

Department of Internal Medicine 2, Faculty of Veterinary Medicine, Okayama University of Science, Imabari, Japan.

出版信息

Vet Med Sci. 2022 Jan;8(1):26-30. doi: 10.1002/vms3.634. Epub 2021 Sep 19.

Abstract

A 36-month-old female Pembroke Welsh Corgi with a cardiac murmur weighing 12.6 kg was referred to the Matsubara Animal Hospital cardiology service. Echocardiography revealed a patent ductus arteriosus. The dog underwent ductus arteriosus closure using an Amplatz Canine Duct Occluder. After the operation, we suspected coagulation and a platelet disorder because of the slightly increased haemorrhage during the operation, postoperative purpura around the surgical wound inside of the thigh, and dog breed, which is known to be commonly affected with von Willebrand disease (vWD). Subsequently, type 1 vWD was confirmed. Complete occlusion was achieved 1 month after the operation; however, 2 months after the operation, recanalization appeared. Recanalization progressed gradually; cardiac redilation was not detected 6 years after the operation. The late recanalization was most likely associated with vWD. In canine breeds pre-disposed to developing vWD, pre-operative testing may be indicated prior to patent ductus arteriosus occlusion, though the prevalence of vWD is rare.

摘要

一只 36 月龄、体重 12.6 公斤的雌性彭布罗克威尔士柯基犬,因心脏杂音被转诊至松原动物医院心脏病学服务中心。超声心动图显示动脉导管未闭。该犬使用 Amplatz 犬动脉导管封堵器进行了动脉导管闭合术。术后,由于手术过程中出血略有增加,大腿内侧手术伤口周围出现术后瘀斑,并且该犬种已知常患有血管性血友病(vWD),我们怀疑存在凝血和血小板功能障碍。随后,确诊为 1 型 vWD。术后 1 个月完全闭塞;然而,术后 2 个月出现再通。再通逐渐进展;术后 6 年未发现心脏扩张。晚期再通很可能与 vWD 有关。在易患 vWD 的犬种中,尽管 vWD 的患病率较低,但在进行动脉导管未闭封堵术前,可能需要进行术前检查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d417/8788971/42a7efb67b6f/VMS3-8-26-g003.jpg

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